Eight serum proteins (P-selectin, E-selectin, IL-2sRα, IL-18, NE, uPA, uPAR, and CRP) that are elevated in infected neonates function in a molecular network.

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Eight serum proteins (P-selectin, E-selectin, IL-2sRα, IL-18, NE, uPA, uPAR, and CRP) that are elevated in infected neonates function in a molecular network that links coagulation/fibrinolysis, cell adhesion, and inflammation, which are critical determinants of the response to systemic infection.Mo/Mφ, monocytes macrophages. Eight serum proteins (P-selectin, E-selectin, IL-2sRα, IL-18, NE, uPA, uPAR, and CRP) that are elevated in infected neonates function in a molecular network that links coagulation/fibrinolysis, cell adhesion, and inflammation, which are critical determinants of the response to systemic infection.Mo/Mφ, monocytes macrophages. Stephen F. Kingsmore et al. Mol Cell Proteomics 2008;7:1863-1875 © 2008 The American Society for Biochemistry and Molecular Biology