Intranasal Condyloma Acuminatum with Malignant Transformation

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Intranasal Condyloma Acuminatum with Malignant Transformation Tengchin Wang, MD, Chiehjen Wu, MD The American Journal of Medicine Volume 130, Issue 11, Pages e503-e504 (November 2017) DOI: 10.1016/j.amjmed.2017.05.016 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure (A) Cauliflower-like lesion growing in the right nasal vestibule and occluding the naris; (B) papillary architecture with hyperkeratosis of the overlying squamous epithelium; (C) koilocytosis, which is characteristic of active viral replication; and (D) invasive carcinoma beyond the basement membrane (black arrow), consisting of irregular nests of hyperchromatic cells showing squamous differentiation and focal mitotic figures (black asterisks). The American Journal of Medicine 2017 130, e503-e504DOI: (10.1016/j.amjmed.2017.05.016) Copyright © 2017 Elsevier Inc. Terms and Conditions