Volume 15, Issue 10, Pages 1009-1010 (September 2016) Role of 18F-FDG-PET imaging in the diagnosis of autoimmune encephalitis Silvia Morbelli, Mehdi Djekidel, Swen Hesse, Marco Pagani, Henryk Barthel The Lancet Neurology Volume 15, Issue 10, Pages 1009-1010 (September 2016) DOI: 10.1016/S1474-4422(16)30140-5 Copyright © 2016 Elsevier Ltd Terms and Conditions
Figure Example of 18F-FDG-PET imaging and MRI findings in a 79-year-old female patient with limbic encephalitis associated with voltage-gated potassium channel complex antibodies (A) 18Fluorodeoxyglucose (18F-FDG) PET imaging shows extensive right medial temporal hypermetabolism and relatively less extensive hypermetabolism in the contralateral medial temporal cortex. (B) Voxel-based comparison of the patient data with an age-matched control group using SPM software confirms the bilateral medial temporal involvement (significant clusters in terms of Z-score are superimposed onto a statistical parametric mapping MRI template). (C) Fluid-attenuated inversion recovery (FLAIR) MRI shows only relative right medial temporal signal hyperintensity. The Lancet Neurology 2016 15, 1009-1010DOI: (10.1016/S1474-4422(16)30140-5) Copyright © 2016 Elsevier Ltd Terms and Conditions