Inflammatory signals associated with hemodialysis

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Presentation transcript:

Inflammatory signals associated with hemodialysis Kayser Caglar, Youming Peng, Lara B. Pupim, Paul J. Flakoll, Deanna Levenhagen, Raymond M. Hakim, T. Alp Ikizler Kidney International Volume 62, Issue 4, Pages 1408-1416 (October 2002) DOI: 10.1111/j.1523-1755.2002.kid556.x Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 1 Experimental design. Each study consisted of a 120-minute equilibration period (-150 to -30 minutes), a 30-minute basal period, a 240-minute hemodialysis period (0 to 240 minutes), and a 120-minute post-dialysis period. The dashes indicate blood sampling time points. Kidney International 2002 62, 1408-1416DOI: (10.1111/j.1523-1755.2002.kid556.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 2 Expired carbon dioxide (CO2) enrichments during the study. The data indicate steady-state conditions during each phase of the study with slopes not statistically significantly different than zero. Kidney International 2002 62, 1408-1416DOI: (10.1111/j.1523-1755.2002.kid556.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 3 (13C)ketoisocaproate (KIC) enrichments during the study period. The data indicate steady-state conditions during each phase of the study with slopes not statistically significantly different than zero. Kidney International 2002 62, 1408-1416DOI: (10.1111/j.1523-1755.2002.kid556.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 4 The increment in interleukin-6 (IL-6) concentration during each study period for each individual patient. The mean is depicted in bold. *Denotes significant difference from the baseline period for the mean (P < 0.05); α denotes P = 0.05 vs. hemodialysis for the mean. Kidney International 2002 62, 1408-1416DOI: (10.1111/j.1523-1755.2002.kid556.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 5 The increment in fibrinogen fractional synthetic rates (FSR) during each study period for each individual patient. The mean is depicted in bold. *Denotes significant difference from the baseline period (P < 0.05) for the mean. Kidney International 2002 62, 1408-1416DOI: (10.1111/j.1523-1755.2002.kid556.x) Copyright © 2002 International Society of Nephrology Terms and Conditions