Decreased weight and adiposity is transmissible via the gut microbiota

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Fig. 6 Decreased weight and adiposity is transmissible via the gut microbiota. Decreased weight and adiposity is transmissible via the gut microbiota. (A) Body weight curves for SHAM-R (n = 6) and RYGB-R (n = 10) mice, represented as change from initial body weight. (B) Change in body weights (BW) among the groups relative to baseline. (C) Cumulative food intake over the 13-day colonization period. (D and E) Visceral fat pad weights (D) and plasma leptin levels (E) in the RYGB-R (n = 10), uninoculated germ-free (n = 7), and consolidated SHAM-R (n = 10) groups. Values in (A) to (E) are means ± SEM. *P < 0.05, **P < 0.01, ANOVA post hoc test. Representative of three experiments. (F) Relative abundance of bacterial taxa in recipient animals after gavage with cecal contents from RYGB, SHAM, and WMS donors. Mean values across each time point (1 to 13 days after gavage) are shown (n = 3 to 15 samples per time point; 10,000 sequences per sample). Alice P. Liou et al., Sci Transl Med 2013;5:178ra41 Published by AAAS