Individual Patient-specific Planning of Minimally Invasive Transcatheter Intervention for Heart Valve Disease A. De Vecchi, S. Niederer, R. Rajani, S.

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Individual Patient-specific Planning of Minimally Invasive Transcatheter Intervention for Heart Valve Disease A. De Vecchi, S. Niederer, R. Rajani, S. Redwood, B. Prendergast EClinicalMedicine Volume 6, Pages 9-10 (December 2018) DOI: 10.1016/j.eclinm.2019.01.002 Copyright © 2019 Terms and Conditions

Fig. 1 Patient-specific planning of minimally invasive transcatheter intervention. A: Overlay of simple valve geometry to CT images accounting for different levels of atrial placement. B: Normal projection of the outflow plane into the left ventricle to measure the proportion of outflow area obstructed by the valve frame. C–F: Finite-element simulation of patient-specific device implantation in a calcified mitral annulus (illustrated in white) with low (C–D) and high probability of LVOT obstruction (E–F). G–H: Patient-specific computational fluid-dynamic simulation of intraventricular pressure (G) and blood flow streamlines coloured according to velocity (H) following device implantation. (Panels A–B and G–H modified from De Vecchi et al. Sci Rep 2018;8:15540) EClinicalMedicine 2018 6, 9-10DOI: (10.1016/j.eclinm.2019.01.002) Copyright © 2019 Terms and Conditions