Temperature Dependence of Cerebral Blood Flow for Isolated Regions of the Brain During Selective Cerebral Perfusion in Pigs Justus T. Strauch, MD, Peter.

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Temperature Dependence of Cerebral Blood Flow for Isolated Regions of the Brain During Selective Cerebral Perfusion in Pigs Justus T. Strauch, MD, Peter L. Haldenwang, MD, Katharina Müllem, Miriam Schmalz, Oliver Liakopoulos, MD, Hildegard Christ, Jürgen H. Fischer, MD, Thorsten Wahlers, MD The Annals of Thoracic Surgery Volume 88, Issue 5, Pages 1506-1513 (November 2009) DOI: 10.1016/j.athoracsur.2009.07.013 Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Pigs brain left hemisphere with marked analyzed regions for calculating cerebral blood flow (CBF): (A) pons; (B) cerebellum; (C) cortex; and (D) hippocampus. The Annals of Thoracic Surgery 2009 88, 1506-1513DOI: (10.1016/j.athoracsur.2009.07.013) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Protocol of the experiment, showing time points at which measurements cited in the tables and figures were taken. No microsphere injection for cerebral blood flow (CBF) calculation at time point 7 due to color overlap. (CPB = cardiopulmonary bypass; HCA = hypothermic circulatory arrest; SCP = selective cerebral perfusion.) The Annals of Thoracic Surgery 2009 88, 1506-1513DOI: (10.1016/j.athoracsur.2009.07.013) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Overall cerebral blood flow (CBF), cerebral vascular resistance (CVR), and cerebral metabolic rate of oxygen (CMRO2) at different time points during the experiment. All values are shown as mean ± standard error. (SCP = selective cerebral perfusion.) The Annals of Thoracic Surgery 2009 88, 1506-1513DOI: (10.1016/j.athoracsur.2009.07.013) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Temperature comparison of cerebral blood flow in absolute values for the four investigated regions of the brain. All values are shown as mean ± standard error. (RBF = regional blood flow; SCP = selective cerebral perfusion.) The Annals of Thoracic Surgery 2009 88, 1506-1513DOI: (10.1016/j.athoracsur.2009.07.013) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions