Pulsed Electromagnetic Fields to Reduce Diabetic Neuropathic Pain and Stimulate Neuronal Repair: A Randomized Controlled Trial  Michael I. Weintraub,

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Presentation transcript:

Pulsed Electromagnetic Fields to Reduce Diabetic Neuropathic Pain and Stimulate Neuronal Repair: A Randomized Controlled Trial  Michael I. Weintraub, MD, David N. Herrmann, MD, A. Gordon Smith, MD, Misha M. Backonja, MD, Steven P. Cole, PhD  Archives of Physical Medicine and Rehabilitation  Volume 90, Issue 7, Pages 1102-1109 (July 2009) DOI: 10.1016/j.apmr.2009.01.019 Copyright © 2009 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 1 The CONSORT diagram revealing enrollment and outcomes. A total of 245 subjects were screened, and 225 were randomized and enrolled. A 13.8% dropout occurred (31/225) with no safety issues. Archives of Physical Medicine and Rehabilitation 2009 90, 1102-1109DOI: (10.1016/j.apmr.2009.01.019) Copyright © 2009 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 2 Device: Body Energizer.a (A), PEMF and/or identical sham demagnetized device. (B), Subject with feet in place. Archives of Physical Medicine and Rehabilitation 2009 90, 1102-1109DOI: (10.1016/j.apmr.2009.01.019) Copyright © 2009 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 3 Biopsy consort. Archives of Physical Medicine and Rehabilitation 2009 90, 1102-1109DOI: (10.1016/j.apmr.2009.01.019) Copyright © 2009 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 4 Number of ENFD distal leg crossings in (A) PEMF and (B) sham groups. Dark lines indicate increase in density from baseline to 3 months; light lines indicate decrease or no change. Archives of Physical Medicine and Rehabilitation 2009 90, 1102-1109DOI: (10.1016/j.apmr.2009.01.019) Copyright © 2009 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 5 Scatterplot of total distal thigh ENFD: increase in ENFD was significantly associated with a decrease in NPS 10 (difference) scores (r=−.53; P=.006). Archives of Physical Medicine and Rehabilitation 2009 90, 1102-1109DOI: (10.1016/j.apmr.2009.01.019) Copyright © 2009 American Congress of Rehabilitation Medicine Terms and Conditions