Optimizing Hematology Analysis: When Physical Prototypes Fail, Simulation Provides the Answers Use hydrodynamic focusing to reduce errors in hematology analysis Simulate the fluid flow, heat transfer, and electric fields inside the micro aperture-electrode counting chamber; use results to optimize device configuration for accurate detection of cell types in blood samples COMSOL News 2014: Damien Isèbe, HORIBA Medical, Montpellier, France Simulation of hydrodynamic focusing, showing how sheath flow (blue surface) directs the sample (red surface) along the central axis of the aperture Simulation results showing the electric field inside the aperture; T1 and T2 indicate particle trajectories along the central axis and at the edge, respectively