Tracking Down the Hedgehog's Lair in the Pancreas Anirban Maitra  Gastroenterology  Volume 138, Issue 3, Pages 823-825 (March 2010) DOI: 10.1053/j.gastro.2010.01.021 Copyright © 2010 AGA Institute Terms and Conditions

Figure 1 Pancreatic duct glands (PDGs) are blind outpouchings originating predominantly from the proximal ductal system, and are characterized by Shh ligand expression and a distinct apomucin profile. A striking expansion of PDGs is observed in the setting of chronic injury, including increased Shh ligand expression. PDGs might contribute to epithelial regeneration and serve as a nidus for pancreatic exocrine neoplasia, particularly neoplasms centered on the proximal ductal system. Gastroenterology 2010 138, 823-825DOI: (10.1053/j.gastro.2010.01.021) Copyright © 2010 AGA Institute Terms and Conditions