Optimal Timing for Elective Early Primary Repair of Tetralogy of Fallot: Analysis of Intermediate Term Outcomes Michael E.A. Cunningham, MD, Mary T.

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Optimal Timing for Elective Early Primary Repair of Tetralogy of Fallot: Analysis of Intermediate Term Outcomes Michael E.A. Cunningham, MD, Mary T. Donofrio, MD, Syed Murfad Peer, MD, David Zurakowski, PhD, Richard A. Jonas, MD, Pranava Sinha, MD The Annals of Thoracic Surgery Volume 103, Issue 3, Pages 845-852 (March 2017) DOI: 10.1016/j.athoracsur.2016.07.020 Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Kaplan-Meier curve demonstrating freedom from reintervention is 68% (95% CI: 54% to 82%) in patients 55 days of age and younger and 87% (95% CI: 80% to 94%) in patients over 55 days of age (log-rank = 6.21, p = 0.013). (CI = confidence interval; TOF = tetralogy of Fallot.) The Annals of Thoracic Surgery 2017 103, 845-852DOI: (10.1016/j.athoracsur.2016.07.020) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Freedom from reintervention for patients who underwent elective primary repair of tetralogy of Fallot stratified by TPS. Darkened symbols indicate surgical reintervention, clear symbols reflect percutaneous reintervention. TPS-1 versus TPS-2 (log-rank = 9.4, p = 0.002); TPS-1 versus TPS-3 (log-rank = 64.5, p < 0.001); TPS-2 versus TPS-3 (log-rank = 25.8, p < 0.001); TPS-1 = optimal technical performance; TPS-2 = adequate technical performance; TPS-3 = inadequate technical performance. (CI = confidence interval; TOF = tetralogy of Fallot; TPS = technical performance score.) The Annals of Thoracic Surgery 2017 103, 845-852DOI: (10.1016/j.athoracsur.2016.07.020) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Probability of reintervention by residual RVOT gradient at primary hospital discharge by logistic regression analysis showing probability of reintervention with increasing residual RVOT gradient. Dashed lines represent 95% confidence interval. (RVOT = right ventricular outflow tract.) The Annals of Thoracic Surgery 2017 103, 845-852DOI: (10.1016/j.athoracsur.2016.07.020) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions