Magnitude and regional distribution of cartilage loss associated with grades of joint space narrowing in radiographic osteoarthritis – data from the Osteoarthritis.

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Magnitude and regional distribution of cartilage loss associated with grades of joint space narrowing in radiographic osteoarthritis – data from the Osteoarthritis Initiative (OAI) F. Eckstein, W. Wirth, D.J. Hunter, A. Guermazi, C.K. Kwoh, D.R. Nelson, O. Benichou Osteoarthritis and Cartilage Volume 18, Issue 6, Pages 760-768 (June 2010) DOI: 10.1016/j.joca.2009.12.009 Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Sagittal DESS images with water excitation showing. a. The vector running parallel to the femoral shaft and through the most posterior point of the trochlear notch (line with small white dashes). b. The plane separating the central, weight-bearing part of the medial femoral condyle [cMF] and the posterior medial femoral condyle (pMF). The line with small white dashes shows the transition between the femoral trochlea and the femoral condyle [MF], as identified in a central slice (see a). The line with large white dashes shows the most posterior aspect of the MF. The solid white line indicates the location where the cMF and the pMF are separated at 75% of the distance between the two white dashed lines. Osteoarthritis and Cartilage 2010 18, 760-768DOI: (10.1016/j.joca.2009.12.009) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 a. Subregions of the central, weight bearing part of the medial femoral condyle (cMF) (14) and of the posterior medial femoral condyle (pMF) – view from posterior. b. Subregions of the medial tibia (MT) (14) – view from superior. c. A–P subregions for the medial femoral condyle (MF) (15) – view from lateral; i=internal, c=central, e=external, a=anterior, p=posterior subregion. Osteoarthritis and Cartilage 2010 18, 760-768DOI: (10.1016/j.joca.2009.12.009) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Mean within-person differences of cartilage thickness (ThCtAB in mm) of the medial femoral condyle (MF) and in each of the overlapping A–P subregions of the MF for knees with medial joint space narrowing (mJSN) grade 1 (n=45), grade 2 (n=21) and grade 3 (n=7), compared to contra-lateral knees with JSN grade 0 [for subregions also Fig. 2(c)]. Osteoarthritis and Cartilage 2010 18, 760-768DOI: (10.1016/j.joca.2009.12.009) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions