Kindr Motors Drive in Meiosis Courtney M. Schroeder, Harmit S. Malik  Cell  Volume 173, Issue 4, Pages 813-815 (May 2018) DOI: 10.1016/j.cell.2018.04.021 Copyright © 2018 Elsevier Inc. Terms and Conditions

Figure 1 The Neofunctionalized Motor Kindr Rapidly Moves Knobs along Microtubules into the Megaspore of Maize (A) The Ab10 chromosome contains a block of heterochromatic 180 bp repeats (a “knob”) that is linked to a gene that yields purple kernels, while the wild-type N10 chromosome encodes a yellow marker. The Ab10 knob is genetically tightly linked to tandemly clustered genes named the Kindr complex. The Kindr kinesin localizes to the knob and drives the rapid movement of the Ab10 chromosome toward the minus-end of microtubules (inset). (B) This transmission advantage leads to an excess of purple-colored kernels indicative of meiotic drive, whereas lack of drive leads to Mendelian segregation (equal numbers of yellow and purple kernels). Image credit: R. Kelly Dawe. Cell 2018 173, 813-815DOI: (10.1016/j.cell.2018.04.021) Copyright © 2018 Elsevier Inc. Terms and Conditions