Spontaneous brain rhythms predict sleep stability in the face of noise

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Spontaneous brain rhythms predict sleep stability in the face of noise Thien Thanh Dang-Vu, Scott M. McKinney, Orfeu M. Buxton, Jo M. Solet, Jeffrey M. Ellenbogen  Current Biology  Volume 20, Issue 15, Pages R626-R627 (August 2010) DOI: 10.1016/j.cub.2010.06.032 Copyright © 2010 Elsevier Ltd Terms and Conditions

Figure 1 Spindle rate predicts sleep stability. (A) Sleep spindles were automatically detected on central EEG channels during a quiet night of sleep. The number of detected events (vertical bars on the bottom line) per minute defined each subject's spindle rate. (B) On two subsequent nights we introduced ten-second noises, initiated at 40 decibels (dB) and presented every thirty seconds in 5 dB increments until the EEG signal was perturbed (arousal, vertical bars on the bottom line). Each colour represents a different sound type; a sample of four is shown here. (C) Observations were pooled among subjects in the lower and upper halves of the spindle rate distribution (ranges 4.57–5.44 and 5.48–6.14 spindles/min, respectively) based on EEG lead C3 during stage N2. Corresponding sleep survival curves were derived from each pool in stage N2 using the Kaplan-Meier (product-limit) method. Current Biology 2010 20, R626-R627DOI: (10.1016/j.cub.2010.06.032) Copyright © 2010 Elsevier Ltd Terms and Conditions