Figure 1 Annual trend in specimen type submitted as first sample for aquaporin-4 immunoglobulin G testing (serum only vs CSF only vs both) from 101,065 patients over a 9-year period Annual trend in specimen type submitted as first sample for aquaporin-4 immunoglobulin G testing (serum only vs CSF only vs both) from 101,065 patients over a 9-year period *Expected values based on number of samples tested by September 15, 2015. Masoud Majed et al. Neurol Neuroimmunol Neuroinflamm 2016;3:e231 © 2016 American Academy of Neurology