High Flow Rates During Modified Ultrafiltration Decrease Cerebral Blood Flow Velocity and Venous Oxygen Saturation in Infants Rosendo A. Rodriguez, MD,

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High Flow Rates During Modified Ultrafiltration Decrease Cerebral Blood Flow Velocity and Venous Oxygen Saturation in Infants Rosendo A. Rodriguez, MD, PhD, Marc Ruel, MD, MPH, Lothar Broecker, CPC, Garry Cornel, MB, BS The Annals of Thoracic Surgery Volume 80, Issue 1, Pages 22-28 (July 2005) DOI: 10.1016/j.athoracsur.2005.01.030 Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Relationship between mean cerebral blood flow velocities (Mean CBFV) and blood flow rates during modified ultrafiltration (MUF) in 31 children (○) after cardiopulmonary bypass. Flow velocities in the middle cerebral artery are expressed in percentages (%) relative to the pre-MUF baseline. Higher blood flow rates of ultrafiltration during MUF were associated with a significant reduction in the middle cerebral artery flow velocities (r = − 0.49; p = 0.005). The horizontal dotted line indicates the baseline (100%) for all patients. The Annals of Thoracic Surgery 2005 80, 22-28DOI: (10.1016/j.athoracsur.2005.01.030) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Relationship between the absolute changes (Δ) in transcranial mixed venous oxygen saturation (rCVOS) and blood flow rates during modified ultrafiltration (MUF) in 31 children (○) after cardiopulmonary bypass. The Δ rCVOS are expressed as the difference between the values of the rCVOS measured before MUF and those recorded at the end of MUF. The use of high blood flow rates during MUF were associated with a significant reduction in the rCVOS as indicated by more negative values on the Δ rCVOS (r = − 0.49; p = 0.005). The horizontal dotted line indicates no absolute change (Δ rCVOS = 0%). The Annals of Thoracic Surgery 2005 80, 22-28DOI: (10.1016/j.athoracsur.2005.01.030) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions