Heart–lung interactions with different ventilatory settings during acute lung injury and hypovolaemia: an experimental study F.J. da Silva Ramos, E.M.

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Heart–lung interactions with different ventilatory settings during acute lung injury and hypovolaemia: an experimental study F.J. da Silva Ramos, E.M. de Oliveira, M Park, G.P.P. Schettino, L.C.P. Azevedo British Journal of Anaesthesia Volume 106, Issue 3, Pages 394-402 (March 2011) DOI: 10.1093/bja/aeq404 Copyright © 2011 The Author(s) Terms and Conditions

Fig 1 Haemodynamic parameters during different ventilatory settings. (a) PPV; (b) SVV; (c) GEF; (d) GEDV; (e) ETVI. *P<0.05 vs initial ventilation; #P<0.05 vs VT 15 ml kg−1 plus PEEP 5 cm H2O; £P<0.05 vs VT 8 ml kg−1 plus PEEP 13 cm H2O; &P<0.05 vs Baseline; $P<0.05 vs ALI (RM-anova with Bonferroni’s correction P<0.0125 and Tukey’s post hoc analysis P<0.05). VT, tidal volume; PPV, pulse pressure variation; SVV, stroke volume variation; GEF, global ejection fraction; GEDV, global end-diastolic volume; ETVI: extravascular lung thermal volume indexed. British Journal of Anaesthesia 2011 106, 394-402DOI: (10.1093/bja/aeq404) Copyright © 2011 The Author(s) Terms and Conditions

Fig 2 ROC curve of haemodynamic variables in hypovolaemia secondary to haemorrhage. (a) Static haemodynamic variables and (b) dynamic haemodynamic variables. GEF, global ejection fraction; PAOP, pulmonary artery occlusion pressure; CVP, central venous pressure; MAP, systemic mean arterial pressure; SPV, systolic pressure variation; PPV, pulse pressure variation; SVV, stroke volume variation. British Journal of Anaesthesia 2011 106, 394-402DOI: (10.1093/bja/aeq404) Copyright © 2011 The Author(s) Terms and Conditions