Electrocardiographic abnormalities and uremic cardiomyopathy

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Electrocardiographic abnormalities and uremic cardiomyopathy Graham A. Stewart, R.O.N. T. Gansevoort, Patrick B. Mark, Esther Rooney, Theresa A. Mcdonagh, Henry J. Dargie, R. Stuart, C. Rodger, Alan G. Jardine, Dr Kidney International Volume 67, Issue 1, Pages 217-226 (January 2005) DOI: 10.1111/j.1523-1755.2005.00072.x Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 1 Main echocardiographic findings (mean and standard deviations) for the study population (squares) and controls (circles). Abbreviations are: LVMI, left ventricular mass index; EF, ejection fraction; FS, fractional shortening; E:A ratio (diastolic function). *P < 0.05 vs. patients with renal disease with near-normal renal function (1st quartile). #P < 0.05 vs. corresponding age- and sex-matched control group. Kidney International 2005 67, 217-226DOI: (10.1111/j.1523-1755.2005.00072.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 2 Left ventricular abnormalities in patients with renal disease. CRF 1–4 are the four groups with primary and progressive renal disease; HD and Tx are the hemodialysis and transplant groups. The upper panel shows the proportion of patients (%) with ECG evidence of LVH. The second panel shows the proportion with echocardiographic evidence of LVH- the hatched bar is eccentric LVH, the open bar concentric LVH. The third panel shows the proportion (%) with dilated cardiomyopathy (DCM), and the bottom panel the proportion (%) with systolic dysfunction (LVSD). Kidney International 2005 67, 217-226DOI: (10.1111/j.1523-1755.2005.00072.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 3 Electrocardiographic findings. QTc is the QT interval in milliseconds, corrected for heart rate19,20, QTcd is corrected QT dispersal, and the lower two panels show the proportion of patients with more than 6 ectopics (VE) per hour on Holter monitoring or the presence of tachyarrhythmias (SVT/VT). The median number of VEs per hour is as follows: CRF1-0.33, CRF2-0.59, CRF3-0.35, CRF4-1.12, HD-1.08, Tx-0.62. Asterisks represent statistical significance: *P < 0.05, **P < 0.01, ***P < 0.001 with respect to CRF group 1. Kidney International 2005 67, 217-226DOI: (10.1111/j.1523-1755.2005.00072.x) Copyright © 2005 International Society of Nephrology Terms and Conditions