Naloxone lowers cerebrospinal fluid levels of excitatory amino acids after thoracoabdominal aortic surgery Takashi Kunihara, MD, PhD, Kenji Matsuzaki,

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Naloxone lowers cerebrospinal fluid levels of excitatory amino acids after thoracoabdominal aortic surgery Takashi Kunihara, MD, PhD, Kenji Matsuzaki, MD, Norihiko Shiiya, MD, PhD, Yasuaki Saijo, MD, PhD, Keishu Yasuda, MD, PhD Journal of Vascular Surgery Volume 40, Issue 4, Pages 681-690 (October 2004) DOI: 10.1016/j.jvs.2004.07.005 Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

Fig 1 Time course of glutamate levels in the cerebrospinal fluid (CSF) in patients with or without postoperative spinal cord injury. All figure error bars represent standard deviation. All data are presented by percent change from baseline. Journal of Vascular Surgery 2004 40, 681-690DOI: (10.1016/j.jvs.2004.07.005) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

Fig 2 Time course of aspartate levels in the cerebrospinal fluid (CSF) in patients with or without postoperative spinal cord injury. Journal of Vascular Surgery 2004 40, 681-690DOI: (10.1016/j.jvs.2004.07.005) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

Fig 3 Time course of glycine levels in the cerebrospinal fluid (CSF) in patients with or without postoperative spinal cord injury. Journal of Vascular Surgery 2004 40, 681-690DOI: (10.1016/j.jvs.2004.07.005) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

Fig 4 Postoperative maximum levels of CSF EAAs for patients with and without spinal cord injury. All data are presented by percent change from baseline. Journal of Vascular Surgery 2004 40, 681-690DOI: (10.1016/j.jvs.2004.07.005) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

Fig 5 Time course of glutamate levels in the cerebrospinal fluid (CSF) in patients given naloxone or not. Journal of Vascular Surgery 2004 40, 681-690DOI: (10.1016/j.jvs.2004.07.005) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

Fig 6 Time course of aspartate levels in the cerebrospinal fluid (CSF) in patients given naloxone or not. Journal of Vascular Surgery 2004 40, 681-690DOI: (10.1016/j.jvs.2004.07.005) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

Fig 7 Time course of glycine levels in the cerebrospinal fluid (CSF) in patients given naloxone or not. Journal of Vascular Surgery 2004 40, 681-690DOI: (10.1016/j.jvs.2004.07.005) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

Fig 8 Postoperative maximum levels of CSF ENAAs compared between patients underwent naloxone-treatment or not. All data are presented by percent change from baseline. Journal of Vascular Surgery 2004 40, 681-690DOI: (10.1016/j.jvs.2004.07.005) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions