The Impact of 22q11.2 Deletion Syndrome on Surgical Repair Outcomes of Conotruncal Cardiac Anomalies Bahaaldin Alsoufi, MD, Courtney McCracken, PhD,

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Presentation transcript:

The Impact of 22q11.2 Deletion Syndrome on Surgical Repair Outcomes of Conotruncal Cardiac Anomalies Bahaaldin Alsoufi, MD, Courtney McCracken, PhD, Subhadra Shashidharan, MD, Shriprasad Deshpande, MD, Kirk Kanter, MD, Brian Kogon, MD The Annals of Thoracic Surgery Volume 104, Issue 5, Pages 1597-1604 (November 2017) DOI: 10.1016/j.athoracsur.2017.04.019 Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Adjusted odds ratios and associated 95% confidence intervals for hospital mortality, extracorporeal membrane oxygenation requirement (ECMO), and unplanned reoperation for the three groups. Models were adjusted for weight, prematurity, sex, and diagnosis. (vs. = versus.) The Annals of Thoracic Surgery 2017 104, 1597-1604DOI: (10.1016/j.athoracsur.2017.04.019) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Adjusted means with associated 95% confidence intervals for postoperative hospital length of stay, intensive care unit (ICU) stay, and duration of mechanical ventilation for the three groups. Models were adjusted for weight, prematurity, sex, and diagnosis. The Annals of Thoracic Surgery 2017 104, 1597-1604DOI: (10.1016/j.athoracsur.2017.04.019) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Parametric model for survival after surgery stratified by the three groups: no genetic or extracardiac condition (black line), 22q.11.2 deletion syndrome (green line), and other genetic syndromes (red line). The Annals of Thoracic Surgery 2017 104, 1597-1604DOI: (10.1016/j.athoracsur.2017.04.019) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Adjusted hazard ratios with associated 95% confidence intervals for overall long-term survival for the three groups. (vs. = versus.) The Annals of Thoracic Surgery 2017 104, 1597-1604DOI: (10.1016/j.athoracsur.2017.04.019) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions