Prescribing antibiotics when the stakes are higher — do GPs prescribe less when patients are pregnant? A retrospective observational study by Guro Haugen.

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Presentation transcript:

Prescribing antibiotics when the stakes are higher — do GPs prescribe less when patients are pregnant? A retrospective observational study by Guro Haugen Fossum, Svein Gjelstad, Kari J Kværner, and Morten Lindbaek Br J Gen Pract Open Volume 2(2):bjgpopen18X101505 July 24, 2018 Copyright © The Authors 2018

Selection of GPs and patients from the Rx-PAD study database and the Norwegian birth registry in the study period December 2004–February 2007. Selection of GPs and patients from the Rx-PAD study database and the Norwegian birth registry in the study period December 2004–February 2007. aGPs with <10 episodes were excluded. RTI = respiratory tract infection. Rx-PAD = Peer Academic Detailing. Guro Haugen Fossum et al. BJGP Open 2018;2:bjgpopen18X101505 Copyright © The Authors 2018

Diagnosis of respiratory tract infection episodes in study period, showing adjusted odds ratio for 'pregnant' and 95% confidence intervals (significant difference in bold and italic, P<0.05). Diagnoses based on ICPC-2: acute upper respiratory tract infections, URTI (R01–05, 07–29, 74, and 80), tonsillitis (R72 and 76), sinusitis (R75), bronchitis (R78), pneumonia (R81), otitis (H01, 71, 72, and 74), and other respiratory tract infections (R71, 77, 82, and 83). N = 18 890 episodes. Diagnosis of respiratory tract infection episodes in study period, showing adjusted odds ratio for 'pregnant' and 95% confidence intervals (significant difference in bold and italic, P<0.05). Diagnoses based on ICPC-2: acute upper respiratory tract infections, URTI (R01–05, 07–29, 74, and 80), tonsillitis (R72 and 76), sinusitis (R75), bronchitis (R78), pneumonia (R81), otitis (H01, 71, 72, and 74), and other respiratory tract infections (R71, 77, 82, and 83). N = 18 890 episodes. Guro Haugen Fossum et al. BJGP Open 2018;2:bjgpopen18X101505 Copyright © The Authors 2018

Antibiotic prescriptions for URTIs in patients who were pregnant during study period showing adjusted odds ratio for 'pregnant' and 95% confidence intervals, (significant difference in bold and italic, P<0.05). N = 18 890 episodes. Antibiotic prescriptions for URTIs in patients who were pregnant during study period showing adjusted odds ratio for 'pregnant' and 95% confidence intervals, (significant difference in bold and italic, P<0.05). N = 18 890 episodes. aCiprofloxacin and cephalosporins. Penicillins WES = penicillins with extended spectrum. Guro Haugen Fossum et al. BJGP Open 2018;2:bjgpopen18X101505 Copyright © The Authors 2018