Figure 3 Correlation of lipid indexes to MRI measures of disease severity in multiple sclerosis Correlation of lipid indexes to MRI measures of disease.

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Figure 3 Correlation of lipid indexes to MRI measures of disease severity in multiple sclerosis Correlation of lipid indexes to MRI measures of disease severity in multiple sclerosis (A) Heatmap in which each column represents an MRI measure and each row represents the correlation to immunoglobulin G serum antibody reactivity to lipids according to a colorimetric scale. (B) Scatter plots depicting the correlation between each lipid index and MRI measures (BPF, GMF, and T2LV) in the discovery set. (C) Scatter plots depicting the correlation between each lipid index and MRI measures (BPF, GMF, and T2LV) in the validation set. BPF = whole brain parenchymal fraction; GMF = cerebral gray matter fraction (see methods section for details); T2LV = cerebral T2 hyperintense lesion volume; WMF = global cerebral white matter fraction. Rohit Bakshi et al. Neurol Neuroimmunol Neuroinflamm 2016;3:e200 © 2016 American Academy of Neurology