Iodine Maps from Subtraction CT or Dual-Energy CT to Detect Pulmonary Emboli with CT Angiography: A Multiple-Observer Study Subtraction CT showed higher.

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Iodine Maps from Subtraction CT or Dual-Energy CT to Detect Pulmonary Emboli with CT Angiography: A Multiple-Observer Study Subtraction CT showed higher specificity (100%) in the detection of pulmonary embolism (PE) compared with CT angiography alone (94%) and dual-energy CT (95%) (P < .001). Iodine maps had a small added value in PE detection compared with CT angiography alone (AUC was 0.094 for dual-energy CT, 0.093 for subtraction CT, and 0.088 for CT angiography; P values ranged from .01 to .03). Reading times did not increase when iodine maps were added to CT angiography (CT angiography alone, 97 seconds; dual-energy CT, 101 seconds; subtraction CT, 99 seconds; P ≥ .41 among techniques). CT angiography (A), subtraction CT (B), and dual-energy CT (C) demonstrates a pulmonary embolism (PE) in the right upper lobe. The iodine maps (B and C) show the large perfusion defect (green circle) that allowed observers to be more suspicious for a PE. Grob D et al. Published Online: May 14, 2019 https://doi.org/10.1148/radiol.2019182666