Topical antifungal treatment of chronic rhinosinusitis with nasal polyps: A randomized, double-blind clinical trial Michael Weschta, MD, Dagmar Rimek,

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Presentation transcript:

Topical antifungal treatment of chronic rhinosinusitis with nasal polyps: A randomized, double-blind clinical trial Michael Weschta, MD, Dagmar Rimek, MD, Marc Formanek, Doreen Polzehl, MD, Andreas Podbielski, MD, PhD, Herbert Riechelmann, MD, PhD Journal of Allergy and Clinical Immunology Volume 113, Issue 6, Pages 1122-1128 (June 2004) DOI: 10.1016/j.jaci.2004.03.038 Copyright © 2004 American Academy of Allergy, Asthma and Immunology Terms and Conditions

Fig 1 Study design. A pretest-posttest double blind control group design was used. Patients were randomly allocated to the 2 treatment arms in this study. Journal of Allergy and Clinical Immunology 2004 113, 1122-1128DOI: (10.1016/j.jaci.2004.03.038) Copyright © 2004 American Academy of Allergy, Asthma and Immunology Terms and Conditions

Fig 2 CT scores (line in box, median; box, interquartile range; whiskers, lower and upper extremes) before and after 8 weeks of treatment with saline (control) or AMB nasal spray. Journal of Allergy and Clinical Immunology 2004 113, 1122-1128DOI: (10.1016/j.jaci.2004.03.038) Copyright © 2004 American Academy of Allergy, Asthma and Immunology Terms and Conditions

Fig 3 Symptom scores (line in box, median; box, interquartile range; whiskers, highest and lowest values excluding outliers; asterisks, outliers) before and after 8 weeks of treatment with saline (control) or AMB nasal spray. Journal of Allergy and Clinical Immunology 2004 113, 1122-1128DOI: (10.1016/j.jaci.2004.03.038) Copyright © 2004 American Academy of Allergy, Asthma and Immunology Terms and Conditions