Plasticity in Olfactory Epithelium: Is It a Sniffer or Shape Shifter?

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Plasticity in Olfactory Epithelium: Is It a Sniffer or Shape Shifter? Arvind Konkimalla, Purushothama Rao Tata Cell Stem Cell Volume 21, Issue 6, Pages 707-708 (December 2017) DOI: 10.1016/j.stem.2017.11.014 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Cell Lineages and Plasticity in Homeostatic and Regenerating Olfactory Epithelium (A) Schematic of the olfactory epithelium (OE). (B) Schematic of the normal lineage trajectories (black arrows) as well as lineage reversions (red arrows) associated with regenerating OE. (C) Schematic of HBC activation following injury. HBCs contribute to all neuronal and non-neuronal cell types during regeneration as shown using red arrows. Abbreviations: Sus, sustentacular cell; mOSN, mature olfactory sensory neuron; iOSN, immature olfactory sensory neuron; INP, immediate neuronal precursor; TAC, transient amplifying cell; MPP, multipotent progenitor; GBC, globose basal cell; HBC, horizontal basal cell; Bowman-D/A, Bowman gland duct or acinar cell. Cell Stem Cell 2017 21, 707-708DOI: (10.1016/j.stem.2017.11.014) Copyright © 2017 Elsevier Inc. Terms and Conditions