Intron 1 and exon 1 alpha estrogen receptor gene polymorphisms in women with endometriosis Hélio Sato, M.D., Ph.D., Naiara C. Nogueira-de-Souza, M.Sc., Ph.D., Paulo D'Amora, M.Sc., Ismael D.C.G. Silva, M.D., Ph.D., Manoel J.B.C. Girão, M.D., Ph.D., Eduardo Schor, M.D., Ph.D. Fertility and Sterility Volume 90, Issue 6, Pages 2086-2090 (December 2008) DOI: 10.1016/j.fertnstert.2007.10.023 Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions
Figure 1 Photograph of an agarose gel stained with ethidium bromide. (A) Lines 1 and 2: wild-type homozygous samples of the single-nucleotide polymorphism (SNP) in intron 1 of the alpha endrogen receptor gene (ER-α) (205 bp and 22 bp); lines 3 and 4: heterozygous samples containing both alleles of the SNP in intron 1 (227, 205, and 22 bp). (B) Lines 1, 2, and 3: heterozygous samples of the SNP in exon 1 of ER-α (288, 198, 121, 90, 53, and 18 bp); line 4: homozygous wild-type sample in exon 1 (198, 121, 90, 53, and 18 bp). Fertility and Sterility 2008 90, 2086-2090DOI: (10.1016/j.fertnstert.2007.10.023) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions