Why did evolution give us allergies?

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Presentation transcript:

Why did evolution give us allergies? Michael Gross  Current Biology  Volume 25, Issue 2, Pages R53-R55 (January 2015) DOI: 10.1016/j.cub.2015.01.002 Copyright © 2015 Terms and Conditions

Helpful helminths: Parasitic worms have been shown to regulate parts of the host immune system and thereby also to suppress allergic responses. Their disappearance from modern life has been linked to the increasing prevalence of allergies. (Image: Wikimedia Commons/CDC.) Current Biology 2015 25, R53-R55DOI: (10.1016/j.cub.2015.01.002) Copyright © 2015 Terms and Conditions

Bug’s life: House dust mites are among the most significant airborne allergens. Studies using specific molecular agents from these tiny arthropods are now providing deeper insights into the molecular mechanisms behind common allergies. (Image: Wikimedia Commons/Gilles San Martin.) Current Biology 2015 25, R53-R55DOI: (10.1016/j.cub.2015.01.002) Copyright © 2015 Terms and Conditions

Fight club: Honey badgers are fierce fighters known to scare off even much bigger predators. Their rich and varied menu includes poisonous snakes, such as the puff adder shown here. It appears that they develop immunity after their first exposure to the venom. A related video can be seen at https://www.youtube.com/watch?v=z0tycmec1fw (photo used with permission from Colleen Begg www.honeybadger.com). Current Biology 2015 25, R53-R55DOI: (10.1016/j.cub.2015.01.002) Copyright © 2015 Terms and Conditions

Breathe in: Asthma is increasing in prevalence, and much research effort is being invested into understanding the underlying reasons for its rise. (Image: Wikimedia Commons/Source: http://www.nhlbi.nih.gov/health/healthtopics/topics/asthma/livingwith.html.) Current Biology 2015 25, R53-R55DOI: (10.1016/j.cub.2015.01.002) Copyright © 2015 Terms and Conditions