A New Computer-Based Evaporimeter System for Rapid and Precise Measurements of Water Diffusion Through Stratum Corneum In Vitro  Lars Norlén, Margareta.

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Presentation transcript:

A New Computer-Based Evaporimeter System for Rapid and Precise Measurements of Water Diffusion Through Stratum Corneum In Vitro  Lars Norlén, Margareta Andersson, Bo Forslind  Journal of Investigative Dermatology  Volume 113, Issue 4, Pages 533-540 (October 1999) DOI: 10.1046/j.1523-1747.1999.00727.x Copyright © 1999 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 Evaporation unit, showing water chamber, mounted SC membrane, evaporimeter probehead. Journal of Investigative Dermatology 1999 113, 533-540DOI: (10.1046/j.1523-1747.1999.00727.x) Copyright © 1999 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 2 Measurement box, containing evaporation unit (Figure 1), basin of saturated solution of CaCl2 × 6H2O, flange system. Journal of Investigative Dermatology 1999 113, 533-540DOI: (10.1046/j.1523-1747.1999.00727.x) Copyright © 1999 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 3 Extraction unit, showing solvent con- tainer, extraction sample holder, sample holder with mounted SC sample. Journal of Investigative Dermatology 1999 113, 533-540DOI: (10.1046/j.1523-1747.1999.00727.x) Copyright © 1999 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 4 Sample holder composed of aluminum with a Teflon button firmly fixing the SC sample. Note that the vertical dimensions are exaggerated to promote visibility. The actual thickness of the complete unit is 1.0 mm. Journal of Investigative Dermatology 1999 113, 533-540DOI: (10.1046/j.1523-1747.1999.00727.x) Copyright © 1999 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 5 Mass transfer of water through an untreated piece of isolated SC as a function of time. The recording was performed at a temperature of 21°C, and a relative humidity of 33%. Journal of Investigative Dermatology 1999 113, 533-540DOI: (10.1046/j.1523-1747.1999.00727.x) Copyright © 1999 The Society for Investigative Dermatology, Inc Terms and Conditions