Jeffrey M. Harris, MD, PhD, Christopher R

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Presentation transcript:

A randomized trial of quilizumab in adults with refractory chronic spontaneous urticaria Jeffrey M. Harris, MD, PhD, Christopher R. Cabanski, PhD, Heleen Scheerens, PhD, Divya Samineni, PhD, Mary S. Bradley, MS, Colette Cochran, BSN, Petra Staubach, MD, Martin Metz, MD, Gordon Sussman, MD, FRCPC, Marcus Maurer, MD Journal of Allergy and Clinical Immunology Volume 138, Issue 6, Pages 1730-1732 (December 2016) DOI: 10.1016/j.jaci.2016.06.023 Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Effect of quilizumab on serum total IgE level from baseline to week 28. One patient from the quilizumab group had baseline and week 28 IgE values of 88 and 1991 IU/mL, respectively (a 2163% change from baseline). Because of the large effect on the mean and SE, we removed this value. Arrows indicate quilizumab doses at weeks 0 and 4. SE, Standard error. Journal of Allergy and Clinical Immunology 2016 138, 1730-1732DOI: (10.1016/j.jaci.2016.06.023) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Journal of Allergy and Clinical Immunology 2016 138, 1730-1732DOI: (10.1016/j.jaci.2016.06.023) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E2 Journal of Allergy and Clinical Immunology 2016 138, 1730-1732DOI: (10.1016/j.jaci.2016.06.023) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E3 Journal of Allergy and Clinical Immunology 2016 138, 1730-1732DOI: (10.1016/j.jaci.2016.06.023) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E4 Journal of Allergy and Clinical Immunology 2016 138, 1730-1732DOI: (10.1016/j.jaci.2016.06.023) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E5 Journal of Allergy and Clinical Immunology 2016 138, 1730-1732DOI: (10.1016/j.jaci.2016.06.023) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E6 Journal of Allergy and Clinical Immunology 2016 138, 1730-1732DOI: (10.1016/j.jaci.2016.06.023) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions