Fertility and Sterility

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Fertility and Sterility CYP1A1, CYP19, and GSTM1 polymorphisms increase the risk of endometriosis Demetrios A Arvanitis, B.Sc., Georgios E Koumantakis, M.D., Anastasia G Goumenou, M.D., Ph.D., Ioannis M Matalliotakis, M.D., Ph.D., Eugenios E Koumantakis, M.D., Ph.D., Demetrios A Spandidos, Ph.D., D.Sc. Fertility and Sterility Volume 79, Pages 702-709 (March 2003) DOI: 10.1016/S0015-0282(02)04817-3

FIGURE 1 Genotyping for CYP1A1 m1 polymorphism. M = 100-bp DNA ladder. Lanes 1–5, PCR products from specimens after MspI digestion. Lanes 1 and 2, CYP1A1 wt/wt, lanes 3 and 4, CYP1A1 wt/m1, lane 5, CYP1A1 m1/m1. Lane 6, undigested PCR product. Arvanitis. CYP1A1, CYP19, and GSTs in endometriosis. Fertil Steril 2003. Fertility and Sterility 2003 79, 702-709DOI: (10.1016/S0015-0282(02)04817-3)

FIGURE 2 Genotyping for CYP19 VNTR in intron 4 (TTTA)n. M = 10-bp DNA ladder. The genotype for each lane is assigned at the bottom of the figure. Arrows on the right indicate the size of the alleles. Arvanitis. CYP1A1, CYP19, and GSTs in endometriosis.Fertil Steril 2003. Fertility and Sterility 2003 79, 702-709DOI: (10.1016/S0015-0282(02)04817-3)

FIGURE 3 Genotyping for GSTM1 (upper panel) and GSTT1 (lower panel) null deletions. In both panels, M = 100-bp DNA ladder. Upper panel, lanes 3–5, GSTM1 [−]; and lanes 1, 2, and 6, GSTM1 [+]. Lower panel, lane 4, GSTT1 [−]; and lanes 1–3, 5, and 6, GSTT1 [+]. Arvanitis. CYP1A1, CYP19, and GSTs in endometriosis. Fertil Steril 2003. Fertility and Sterility 2003 79, 702-709DOI: (10.1016/S0015-0282(02)04817-3)