Influence of variations in arterial PCO2 on surgical conditions during laparoscopic retroperitoneal surgery  M. Boon, C. Martini, M. Hellinga, R. Bevers,

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Presentation transcript:

Influence of variations in arterial PCO2 on surgical conditions during laparoscopic retroperitoneal surgery  M. Boon, C. Martini, M. Hellinga, R. Bevers, L. Aarts, A. Dahan  British Journal of Anaesthesia  Volume 117, Issue 1, Pages 59-65 (July 2016) DOI: 10.1093/bja/aew114 Copyright © 2016 The Author(s) Terms and Conditions

Fig 1 Flow chart of the study. British Journal of Anaesthesia 2016 117, 59-65DOI: (10.1093/bja/aew114) Copyright © 2016 The Author(s) Terms and Conditions

Fig 2 (a) Individual end-tidal P C O 2 values over time. Blue lines hypocapnia, orange lines hypercapnia. (b) Individual mean end-tidal and arterial P C O 2 values and mean of the means (sd). *P<0.001. (c and d) Profiles of the arterial P C O 2 , end-tidal P C O 2 and difference between arterial and end-tidal P C O 2 ( Δ P C O 2 ) under hypocapnic (c) and hypercapnic conditions (d). Data are mean (95% confidence interval). British Journal of Anaesthesia 2016 117, 59-65DOI: (10.1093/bja/aew114) Copyright © 2016 The Author(s) Terms and Conditions

Fig 3 (a) Mean (95% confidence interval) Leiden-Surgical Rating Scale (L-SRS) scores against time under hypocapnic (blue symbols) and hypercapnic conditions (green symbols). (b) Individual mean L-SRS scores (each symbol is the mean L-SRS of one patient) and mean of the means (sd). In pink the results of the BLISS 1 study performed under normocapnic conditions (arterial P C O 2 6 kPa or 45 mm Hg). (c) Distribution of the surgical ratings under hypocapnic (blue bars) and hypercapnic (green bars) conditions. (d) Individual mean L-SRS scores vs mean individual end-tidal P C O 2 values in subjects treated with hypocapnia (blue symbol) and hypercapnia (green symbol). Pearson r=0.02, P=0.9. British Journal of Anaesthesia 2016 117, 59-65DOI: (10.1093/bja/aew114) Copyright © 2016 The Author(s) Terms and Conditions