Volume 77, Issue 4, Pages (February 2010)

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Presentation transcript:

Volume 77, Issue 4, Pages 265-266 (February 2010) Journal Club Kidney International Volume 77, Issue 4, Pages 265-266 (February 2010) DOI: 10.1038/ki.2009.520 Copyright © 2010 International Society of Nephrology Terms and Conditions

Gla-rich protein is highly accumulated in the human vascular system at sites of pathological calcification of human arteries from both chronic kidney disease patients (a–d) and postmortem samples (e–h). Kidney International 2010 77, 265-266DOI: (10.1038/ki.2009.520) Copyright © 2010 International Society of Nephrology Terms and Conditions

The need to conserve water and the need to conserve sodium work in synergy to set ENaC activity in the collecting duct. Left: Open probability (Po) of the epithelial sodium channel. Right: Number of channels in principal cells from collecting ducts isolated from animals fed a high-Na+ or nominally Na+-free diet with free and restricted access to water. Kidney International 2010 77, 265-266DOI: (10.1038/ki.2009.520) Copyright © 2010 International Society of Nephrology Terms and Conditions

SAP inhibits kidney fibrosis after unilateral ureteral obstruction (UUO). Photomicrograph of Sirius red stain or GFP immunofluorescence of day 14 UUO kidneys. Abbreviations: GFP, green fluorescent protein; HSA, human serum albumin; hSAP, human serum amyloid P. Kidney International 2010 77, 265-266DOI: (10.1038/ki.2009.520) Copyright © 2010 International Society of Nephrology Terms and Conditions