Monocyte Tissue Factor Expression and Ongoing Complement Generation in Ventricular Assist Device Patients Carl R. Wilhelm, Julianne Ristich, Robert L.

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Presentation transcript:

Monocyte Tissue Factor Expression and Ongoing Complement Generation in Ventricular Assist Device Patients Carl R. Wilhelm, Julianne Ristich, Robert L. Kormos, William R. Wagner The Annals of Thoracic Surgery Volume 65, Issue 4, Pages 1071-1076 (April 1998) DOI: 10.1016/S0003-4975(98)00111-8

Fig. 1 Plasma thrombin–antithrombin III complex (TAT) concentration before and during the course of ventricular assist device support (mean + standard error of the mean; n for each postoperative day is indicated). (∗p < 0.05 versus normal data; ∗∗p < 0.05 versus preoperative levels.) The Annals of Thoracic Surgery 1998 65, 1071-1076DOI: (10.1016/S0003-4975(98)00111-8)

Fig. 2 Plasma C3a concentration before and during the course of ventricular assist device support (mean + standard error of the mean). (∗p < 0.05 versus normal data; ∗∗p < 0.05 versus preoperative levels.) The Annals of Thoracic Surgery 1998 65, 1071-1076DOI: (10.1016/S0003-4975(98)00111-8)

Fig. 3 Plasma SC5b-9 concentration before and during the course of ventricular assist device support (mean + standard error of the mean). (∗p < 0.05 versus normal data.) The Annals of Thoracic Surgery 1998 65, 1071-1076DOI: (10.1016/S0003-4975(98)00111-8)

Fig. 4 Monocyte tissue factor (TF) expression measured by flow cytometry (mean + standard error of the mean). (∗p < 0.05 versus normal data.) The Annals of Thoracic Surgery 1998 65, 1071-1076DOI: (10.1016/S0003-4975(98)00111-8)

Fig. 5 Monocyte–platelet microaggregate formation, indicated by CD42b (platelet marker)-positive monocytes as measured by flow cytometry (mean + standard error of the mean). (∗p < 0.05 versus normal data.) The Annals of Thoracic Surgery 1998 65, 1071-1076DOI: (10.1016/S0003-4975(98)00111-8)

Fig. 6 Granulocyte–platelet microaggregate formation, indicated by CD42b-positive granulocytes as measured by flow cytometry (mean + standard error of the mean). (∗p < 0.05 versus normal data.) The Annals of Thoracic Surgery 1998 65, 1071-1076DOI: (10.1016/S0003-4975(98)00111-8)

Fig. 7 The correlation coefficient between granulocyte–platelet conjugates (indicated by CD42b-positive granulocytes) and plasma SCb5-9 levels in ventricular assist device patient blood samples was calculated using ranked data (Spearman R = 0.66; p < 0.001; n = 77). The Annals of Thoracic Surgery 1998 65, 1071-1076DOI: (10.1016/S0003-4975(98)00111-8)