Polyunsaturated fatty acids in plasma at 8 years and subsequent allergic disease Jessica Magnusson, PhD, Sandra Ekström, MSc, Inger Kull, PhD, Niclas.

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Presentation transcript:

Polyunsaturated fatty acids in plasma at 8 years and subsequent allergic disease Jessica Magnusson, PhD, Sandra Ekström, MSc, Inger Kull, PhD, Niclas Håkansson, PhD, Sara Nilsson, MSc, Magnus Wickman, MD, PhD, Erik Melén, MD, PhD, Ulf Risérus, PhD, Anna Bergström, PhD Journal of Allergy and Clinical Immunology Volume 142, Issue 2, Pages 510-516.e6 (August 2018) DOI: 10.1016/j.jaci.2017.09.023 Copyright © 2017 The Authors Terms and Conditions

Fig 1 Flow chart of subjects from the birth cohort BAMSE (Children, Allergy, Milieu, Stockholm, Epidemiology) outlining the inclusion for analyses of fatty acid proportions in plasma phospholipids. Journal of Allergy and Clinical Immunology 2018 142, 510-516.e6DOI: (10.1016/j.jaci.2017.09.023) Copyright © 2017 The Authors Terms and Conditions

Fig 2 Adjusted ORs for prevalent asthma at age 16 years in relation to continuous proportions of AA in plasma at age 8 years. ORs and 95% CIs were calculated with a restricted cubic spline model with 4 knots (represented by black vertical lines) and adjusted for allergic heredity and sex. The red line represents the median proportion of AA. Journal of Allergy and Clinical Immunology 2018 142, 510-516.e6DOI: (10.1016/j.jaci.2017.09.023) Copyright © 2017 The Authors Terms and Conditions

Fig 3 Adjusted ORs for phenotypes of prevalent asthma and rhinitis at age 16 years in relation to continuous proportions of total VLC n-3 (A) and AA (B) in plasma at age 8 years. ORs and 95% CIs were estimated with multinomial logistic regression models adjusted for allergic heredity and sex. Journal of Allergy and Clinical Immunology 2018 142, 510-516.e6DOI: (10.1016/j.jaci.2017.09.023) Copyright © 2017 The Authors Terms and Conditions