Investigations in generalized osteoarthritis

Slides:

Advertisements

Similar presentations

Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis A. Loyola-Sánchez, J. Richardson, N.J.

Advertisements

The association between metacarpal ratio, radiographic hand and knee osteoarthritis and its progression after meniscectomy P.T. Paradowski, L.S. Lohmander,

Corrigendum to ‘The importance of dose in land-based supervised exercise for people with hip osteoarthritis. A systematic review and meta-analysis’ [Osteoarthritis.

Understanding the pain experience in hip and knee osteoarthritis – an OARSI/OMERACT initiative G.A. Hawker, M.D., M.Sc., L. Stewart, M.Sc., M.R. French,

The epidemiology and impact of pain in osteoarthritis

P.-S. Hsu, H.-H. Lin, C.-R. Li, W.-S. Chung

Cross-cultural adaptation of the Dutch version of the Functional Index for Hand Osteoarthritis (FIHOA) and a study on its construct validity R. Wittoek,

Changes in social isolation and loneliness following total hip and knee arthroplasty: longitudinal analysis of the English Longitudinal Study of Ageing.

Osteoarthritis as a disease of mechanics

Does land-based exercise reduce pain and disability associated with hip osteoarthritis? A meta-analysis of randomized controlled trials M. Fransen, S.

Association of knee pain with a reduction in thigh muscle strength – a cross-sectional analysis including 4553 osteoarthritis initiative participants

J. Duryea, Ph. D. , G. Neumann, M. D. , M. H. Brem, M. D. , W. Koh, M

Osteoarthritis year 2011 in review: biochemical markers of osteoarthritis: an overview of research and initiatives Y. Henrotin Osteoarthritis and Cartilage

K. Zou, M.D., G. Liu, M.D., T. Wu, M.D., L. Du, M.D.

C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort study G. Engström, M.D., Ph.D.,

Transdermal buprenorphine plus oral paracetamol vs an oral codeine-paracetamol combination for osteoarthritis of hip and/or knee: a randomised trial

Incidence of symptomatic osteochondritis dissecans lesions of the knee: a population- based study in Olmsted County A. Pareek, T.L. Sanders, I.T. Wu,

Efficacy and safety of intraarticular hyaluronic acid in the treatment of hip osteoarthritis: a systematic review J.C. Fernández López, M.D., Ph.D.,

Characterization of pro-apoptotic and matrix-degradative gene expression following induction of osteoarthritis in mature and aged rabbits Dr. C.M. Robertson,

Osteoarthritis year 2013 in review: genetics and genomics

Time to be positive about negative data?

J. Avouac, M.D., L. Gossec, M.D., M. Dougados, M.D.

L. Kalichman, P.T., Ph.D., I. Malkin, Ph.D., E. Kobyliansky, Ph.D.

Gene expression variation in human meniscus: molecular and clinical implications for cartilage homeostasis and early osteoarthritis development M.F.

Stem cell therapy for human cartilage defects: a systematic review

S. Sonne-Holm, M.D., Dr. Sci., S. Jacobsen, M.D.

N.D. Miljkovic, M.D., Ph.D., G.M. Cooper, Ph.D., K.G. Marra, Ph.D.

Risk factors associated with reduced work productivity among people with chronic knee pain M. Agaliotis, M. Fransen, L. Bridgett, L. Nairn, M. Votrubec,

J. Ranstam Osteoarthritis and Cartilage

Sampling uncertainty in medical research

Effectiveness of thermal and athermal short-wave diathermy for the management of knee osteoarthritis: a systematic review and meta-analysis Y. Laufer,

The role of sequence variations within the genes encoding collagen II, IX and XI in non- syndromic, early-onset osteoarthritis E. Jakkula, M.D., M. Melkoniemi,

High hand joint mobility is associated with radiological CMC1 osteoarthritis: the AGES- Reykjavik study H. Jónsson, G.J. Elíasson, Á. Jónsson, G. Eiríksdóttir,

Osteoarthritis of the knee after meniscal resection: long term radiographic evaluation of disease progression P.T. Paradowski, L.S. Lohmander, M. Englund

Utilization rates of hip arthroplasty in OECD countries

Scientific production and impact of national registers: the example of orthopaedic national registers P. Boyer, I. Boutron, P. Ravaud Osteoarthritis.

M.D. Westby, D.A. Marshall, C.A. Jones Osteoarthritis and Cartilage

Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis M. Blagojevic, C. Jinks, A. Jeffery, K.P.

A graphic user interface for the evaluation of knee osteoarthritis (GEKO): an open- source tool for histological grading H.E. Kloefkorn, B.Y. Jacobs,

Who should have a joint replacement? A plea for more ‘phronesis’

Knee Injury and Osteoarthritis Outcome Score (KOOS): systematic review and meta- analysis of measurement properties N.J. Collins, C.A.C. Prinsen, R. Christensen,

Validation of a self-report instrument for assessment of hallux valgus

D.J. Hunter Osteoarthritis and Cartilage

L. Shan, B. Shan, D. Graham, A. Saxena Osteoarthritis and Cartilage

S. Kobayashi, E. Pappas, M. Fransen, K. Refshauge, M. Simic

S.G. Muthuri, D.F. McWilliams, M. Doherty, W. Zhang

Confirmation of two major polyarticular osteoarthritis (POA) phenotypes – differentiation on the basis of joint topography G.J. Carroll, W.H. Breidahl,

Limited effects of exercises in people with hand osteoarthritis: results from a randomized controlled trial N. Østerås, K.B. Hagen, M. Grotle, A.-L.

Most patients gain weight in the 2 years after total knee arthroplasty: comparison to a healthy control group J.A. Zeni, L. Snyder-Mackler Osteoarthritis.

Body mass index and alignment and their interaction as risk factors for progression of knees with radiographic signs of osteoarthritis E. Yusuf, J. Bijsterbosch,

F. Zhang, Ph. D. , G. Zhai, Ph. D. , B. S. Kato, Ph. D. , D. J

C. Ratzlaff, M. Koehoorn, J. Cibere, J. Kopec

I. G. Otterness, Ph. D. , M. -P. H. Le Graverand, M. D. , Ph. D. , F

T. Silvestri, M. D. , L. Pulsatelli, Ph. D. , P. Dolzani, Ph. D. , A

Falls risk is associated with pain and dysfunction but not radiographic osteoarthritis in older adults: Tasmanian Older Adult Cohort study S.J. Foley,

Development and preliminary evaluation of the OsteoArthritis Questionnaire (OA- Quest): a psychometric study L. Busija, R. Buchbinder, R.H. Osborne Osteoarthritis.

N. Frey, T. Hügle, S.S. Jick, C.R. Meier, J. Spoendlin

Osteoarthritis year 2012 in review: biology

Osteoarthritis year in review 2015: biology

Location-specific hip joint space width for progression of hip osteoarthritis – Data from the Osteoarthritis Initiative C. Ratzlaff, C. Van Wyngaarden,

Investigations in generalized osteoarthritis

S. Wei, A. Venn, C. Ding, J. Martel-Pelletier, J. -P. Pelletier, F

Systematic review of the impact of osteoarthritis on health outcomes for comorbid disease in older people L. Parkinson, D.L. Waters, L. Franck Osteoarthritis.

Self-management and peer support among people with arthritis on a hospital joint replacement waiting list: a randomised controlled trial M. Crotty, J.

Erratum to “Effect of hyaluronic acid (MW 500–730kDa) on proteoglycan and nitric oxide production in human osteoarthritic chondrocyte cultures exposed.

Osteoarthritis year in review 2016: mechanics

Familial osteochondritis dissecans associated with early osteoarthritis and disproportionate short stature E.-L. Stattin, M.D., Y. Tegner, M.D., Ph.D.,

Changes in pain, stiffness and physical function in patients with osteoarthritis waiting for hip or knee joint replacement surgery H. Kapstad, R.N.,

M. Doherty, P. Dieppe Osteoarthritis and Cartilage

General Information Osteoarthritis and Cartilage

Presentation transcript:

Investigations in generalized osteoarthritis Investigations in generalized osteoarthritis. Part 1: Genetic study of Heberden's nodes U. Irlenbusch, M.D., Th. Schäller Osteoarthritis and Cartilage Volume 14, Issue 5, Pages 423-427 (May 2006) DOI: 10.1016/j.joca.2005.11.016 Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Fig. 1 Fictitious clan table of 93 index cases with 156 descendants: ♦ total, □ male, and ○ female. White signs: healthy till now. Black signs: manifest affected. Osteoarthritis and Cartilage 2006 14, 423-427DOI: (10.1016/j.joca.2005.11.016) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Fig. 2 Combination square in monomeric inheritance for heterozygous–homozygous parents. H=gene for trait Heberden's arthritis and h=normal gene. Osteoarthritis and Cartilage 2006 14, 423-427DOI: (10.1016/j.joca.2005.11.016) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Fig. 3 Age pattern of the daughters of the index cases. Osteoarthritis and Cartilage 2006 14, 423-427DOI: (10.1016/j.joca.2005.11.016) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions