Differential modulation of interleukin‐6 and interleukin‐10 by diclofenac in patients undergoing major surgery A.M. Mahdy, H.F. Galley, M.A. Abdel‐Wahed,

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Presentation transcript:

Differential modulation of interleukin‐6 and interleukin‐10 by diclofenac in patients undergoing major surgery A.M. Mahdy, H.F. Galley, M.A. Abdel‐Wahed, K.F. El‐Korny, S.A. Sheta, N.R. Webster British Journal of Anaesthesia Volume 88, Issue 6, Pages 797-802 (June 2002) DOI: 10.1093/bja/88.6.797 Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

Fig 1 Changes in circulating IL‐6 concentrations during major urological surgery in patients treated with diclofenac (P<0.0001, Friedman analysis of variance) and those treated with placebo (P<0.0001, Friedman analysis of variance). Box and whisker plot showing median, 25th and 75th percentiles and range. **P<0.001 compared with basal (before surgery). British Journal of Anaesthesia 2002 88, 797-802DOI: (10.1093/bja/88.6.797) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

Fig 2 Changes in circulating IL‐10 concentrations during major urological surgery in patients treated with diclofenac (P<0.0001, Friedman analysis of variance) and those treated with placebo (P<0.0001, Friedman analysis of variance). Box and whisker plot showing median, 25th and 75th percentiles and range. *P<0.01 and **P<0.001 compared with basal (before surgery). British Journal of Anaesthesia 2002 88, 797-802DOI: (10.1093/bja/88.6.797) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

Fig 3 Changes in circulating cortisol concentrations during major urological surgery in patients treated with diclofenac (P<0.0001, Friedman analysis of variance) and those treated with placebo (P<0.0001, Friedman analysis of variance). Box and whisker plot showing median, 25th and 75th percentiles and range. *P<0.01 and **P<0.001 compared with basal (before surgery). British Journal of Anaesthesia 2002 88, 797-802DOI: (10.1093/bja/88.6.797) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions