Ability of stroke volume variation measured by oesophageal Doppler monitoring to predict fluid responsiveness during surgery P.-G. Guinot, B. de Broca,

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Ability of stroke volume variation measured by oesophageal Doppler monitoring to predict fluid responsiveness during surgery P.-G. Guinot, B. de Broca, O. Abou Arab, M. Diouf, L. Badoux, E. Bernard, E. Lorne, H. Dupont British Journal of Anaesthesia Volume 110, Issue 1, Pages 28-33 (January 2013) DOI: 10.1093/bja/aes301 Copyright © 2013 The Author(s) Terms and Conditions

Fig 1 ROC curves of FTc, ΔrespSV, and ΔrespPV to discriminate responders and non-responders to VE. Area under ROC appears in cartouche with 95% confidence interval (95% CI). British Journal of Anaesthesia 2013 110, 28-33DOI: (10.1093/bja/aes301) Copyright © 2013 The Author(s) Terms and Conditions

Fig 2 Box and whisker plot represents the distribution of baseline FTc according to each group (responders and non-responders). Baseline FTc was not statistically different between the two groups. FTc, corrected flow time expressed as ms. British Journal of Anaesthesia 2013 110, 28-33DOI: (10.1093/bja/aes301) Copyright © 2013 The Author(s) Terms and Conditions

Fig 3 Determination of the grey zone for ΔrespSV according to an optimal threshold (cost ratio: R=1). The grey zone approach indicated two cut-offs between which the diagnosis of fluid responsiveness remains uncertain. The grey zone was calculated using two approaches. (a) Histograms represent the distribution of the optimal cut-offs for each of the 1000 resampled population. The black line indicates the median of the distribution of optimal thresholds. The inconclusive zone (95% CI) is represented as a shaded zone. (b) Two graph ROC curves: sensitivity (Se) and specificity (Sp) of ΔrespSV according to the value of the cut-off. The inconclusive zone, which is more than 10% of diagnosis tolerance, is represented as a shaded zone. British Journal of Anaesthesia 2013 110, 28-33DOI: (10.1093/bja/aes301) Copyright © 2013 The Author(s) Terms and Conditions