Opening Activity: February 25, 2018 Welcome BACK! If you forget where you sit, come see me. Pick up ONE rubric for your Hamilton Take Charge Group from front table. How did something you do over the break relate to growth and development? Share at your table. Who remembers what we did on the Friday before break? Homework: Hamilton Take Charge – Due 2/26 Human Energy Systems Retake Friday March 1st @ 8am or another pre-arranged time. I can… Model Cell Division

Lab #13 Modeling Cell Division Part B How would you describe the shape of chromosomes under the microscope? What happens to the nuclear membrane in the first few steps of cell division? .

Lab #13 Modeling Cell Division Question: How does a single cell develop into a body with more than a trillion cells, each with the same genetic information? Goal: Use whiteboards, pens, pipecleaners and worksheet to model cell division. Stamp on #3 Stamp when complete Check on planaria for LAST measurement

Last Planaria Check Take final measurements and observations. When recording observations think about: a. Organism Scale: ​ Physical Characteristics​ and behaviors​ b. Cellular Scale: ​ Cell structures or functions​ and number of cells​ c. Molecular Scale: ​ Specific DNA sequences​, Genes​, other molecules​ ​2. Record data and observations in journal. Return Planaria to the “Recovery Container”. Return petri dishes to white tub at supply area.

Opening Activity: February 26, 2018 Attach your Hamilton Takes Charge Rubric – and turn into basket OR front of classroom (if big). Review your Lab #13 – Modeling Cell Division. Check that you have two stamps, #3 and #8. If not, let Ms. Fox know so she can stamp you! Pick up a Learning Tracking Tool at front table. Fill out the first line for “Card Sort and Modeling Cell Division”. Review the personality inventory at your table – which one are you? I can… Reflect on the purpose of cell division and describe DNA Homework: Human Energy Systems Retake Friday March 1st @ 8am DNA Coloring

DNA = Deoxyribonucleic Acid STORES GENETIC INFORMATION Organic Molecule Example of a polymer

Comparing DNA to other Biomolecules Atoms # of atoms in one molecule Glucose C, H, O 24 Starch ~1000 Phospholipids 120 Protein C, H, O,N 500,000 DNA

DNA is arranged into polymers called chromosomes (built from nucleotide monomers) Chromosomes can get packed together to take up less space Chromosome = single molecule of DNA

Be prepared to make a DNA molecule tomorrow! Homework due 2/27 Color and cut your nucleotides. Adenine (A) = red Cytosine (C) = blue Guanine (G) = green Thymine (T) = yellow Sugar = orange Phosphate = purple Be prepared to make a DNA molecule tomorrow!

Opening Activity: Feb. 27, 2018 Create a new page in your journal title it “LAB #14 DNA Models”. Have your models out to show. I will stamp your journal for having models complete. Pick up DNA Reading guide at front table - read, highlight, underline, etc. – up to first paragraph on 2nd page. What is the DNA monomer and polymer called? What are the three parts of a nucleotide? How does complimentary base pairing work? Answer in Lab #14 Section I can… Construct a DNA model and identify the 4 nucleotides that make up DNA. Homework: Human Energy Systems Retake Friday March 1st @ 8am

DNA forms a double helix Learn more about Rosalind Franklin’s role in the discovery of DNA by watching this video: https://www.youtube.com/watch?v=BIP0lYrdirI

DNA forms a double helix James Watson & Francis Crick Learn more about Rosalind Franklin’s role in the discovery of DNA by watching this video: https://www.youtube.com/watch?v=BIP0lYrdirI

DNA is made of monomers called nucleotides

DNA is made of monomers called nucleotides Adenine (A) Guanine (G) Pairs to  Thymine (T) Cytosine (C)

Nucleotides always pair specifically = complementary base pairing Teacher Notes: This is a great opportunity to act out DNA base pairing! A - T C - G Science theater!

Building DNA DNA is double stranded The nucleotides on one strand COMPLEMENTS the nucleotides on the other strand = complementary base-pairing G-C and A-T

Lab #14 Modeling DNA Procedure: Create a DNA molecule, use procedure and reading at your table. TAPE YOUR MOLECULE TOGETHER!! Wrap-up: SKETCH your molecule in your journal, create a key to identify the different molecules that make up DNA. Circle a Guanine Nucleotide. Answer questions: In lab journal. When WHOLE group is done, quiz and stamp! HW: Read the “DNA is Self-Replicating” paragraph in the reading. Write down the steps for DNA Replication

Let’s make a double helix! Color the parts of the nucleotide monomers as follows: Adenine (A) = red Cytosine (C) = blue Guanine (G) = green Thymine (T) = yellow Sugar = orange Phosphate = purple Color and cut out each of the monomers. Link monomers (biosynthesis) to build chromosomes. The left side of your double helix should spell CAT. Use the remaining nucleotide monomers to finish the complementary strand of the double helix. *You may not want to tape until you are certain of the arrangement*

Opening Activity: March 1, 2018 Pick up your DNA molecule from front of room to complete Lab #14. Check your work that you have your sketch in your journal AND answers to #7 a-e. I will stamp on Friday. Read the “DNA is Self-Replicating” paragraph in the reading. Write down the steps for DNA Replication. I can… Homework: Human Energy Systems Retake Friday March 1st @ 8am Development Test 3/7

Recall steps 1&2 from modeling of mitosis This slide refers back to the activity students complete the day before Step 2 Step 1 How did the DNA go from a single chromosomes to replicated chromosomes?

How would you make a copy of your chromosome? How does the new DNA strand compare to the original?

DNA Replication Teacher Notes: This is a great opportunity to act out DNA replication!

Why is it important that DNA makes an exact copy of itself?

DNA Replication Review DNA Splits in half New nucleotides come in and pair up on each half Final product is two IDENTICAL strands of DNA Why do cells want two identical strands of DNA?

Homework DUE 3/1 Learning Tracking Tool: Complete Row 2 for DNA Work DNA Modeling and DNA Replication

Last Planaria Check Take final measurements and observations. When recording observations think about: a. Organism Scale: ​ Physical Characteristics​ and behaviors​ b. Cellular Scale: ​ Cell structures or functions​ and number of cells​ c. Molecular Scale: ​ Specific DNA sequences​, Genes​, other molecules​ ​2. Record data and observations in journal. Return Planaria to the “Recovery Container”. Return petri dishes to white tub at supply area.

Opening Activity: March 1, 2018 Have LTT and Lab #14 Ready for Stamp! Take final measurements and observations. When recording observations think about: a. Organism Scale: ​Physical Char. & behaviors​ b. Cellular Scale: ​Cell structure/function​, # of cells.​ c. Molecular Scale: ​ Specific DNA sequences​, Genes​, other molecules​ ​2. Record data and observations in journal. Return Planaria to the “Recovery Container”. Return petri dishes to white tub at supply area. I can…Explain how cells become specific types of cells Homework: Color your cell for Monday 3/4 Development Test 3/7

The right gene at the right time Cell Differentiation The right gene at the right time

A chromosome has thousands of genes A gene is a region of the chromosome which contains information for making a protein gene chromosome A chromosome has thousands of genes

Key Questions… How do cells know what type of cell to become? How do they coordinate to form tissues, organs, and a complete organism?

What makes the different types of cells in your body unique? Muscle cells and neurons in your body have the same DNA, but they express (use) different genes. Gene expression causes cells to look unique and to perform different functions.

Cell Differentiation Activity Read the introduction to the activity. Review your chromosome, color according to the key. Form a group with all 4 cell types – bone, muscle, stomach and skin. Write their names on your paper. Work together as a group of 4 to review the cells and answer the analysis questions. STAMP!!