Characteristics and long-term outcomes of contemporary patients with bicuspid aortic valves Ahmad Masri, MD, Vidyasagar Kalahasti, MD, Saqer Alkharabsheh,

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Presentation transcript:

Characteristics and long-term outcomes of contemporary patients with bicuspid aortic valves Ahmad Masri, MD, Vidyasagar Kalahasti, MD, Saqer Alkharabsheh, MD, Lars G. Svensson, MD, PhD, Joseph F. Sabik, MD, Eric E. Roselli, MD, Donald Hammer, MD, Douglas R. Johnston, MD, Patrick Collier, MD, PhD, L. Leonardo Rodriguez, MD, Brian P. Griffin, MD, Milind Y. Desai, MD The Journal of Thoracic and Cardiovascular Surgery Volume 151, Issue 6, Pages 1650-1659.e1 (June 2016) DOI: 10.1016/j.jtcvs.2015.12.019 Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Kaplan-Meier survival curves of the study population, separated based on whether patients had surgery related to bicuspid aortic valve (BAV) or not compared with age- and gender-matched US population. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 1650-1659.e1DOI: (10.1016/j.jtcvs.2015.12.019) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Incremental utility of BAV risk score, aortic root size, and BAV surgery. Results were similar if ascending aortic dimensions were entered into the model instead of aortic root dimensions. BAV, Bicuspid aortic valve. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 1650-1659.e1DOI: (10.1016/j.jtcvs.2015.12.019) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Hazard ratios (with 95% confidence intervals) for primary events, plotted against various ascending aortic (root or proximal ascending) cutoffs for undergoing concomitant AAR. The figure demonstrates that an aortic size ≥4.5 cm with no concomitant AAR was associated with a higher hazard for primary events. However, if a cutoff of ≥4 cm was used for ascending aortic surgery, the association with primary events was not significant. The reference group was made up of those with aortic dimensions ≤4 cm. HR, Hazard ratio. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 1650-1659.e1DOI: (10.1016/j.jtcvs.2015.12.019) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Outcomes in BAV for patients who had, versus did not have, surgery. The Journal of Thoracic and Cardiovascular Surgery 2016 151, 1650-1659.e1DOI: (10.1016/j.jtcvs.2015.12.019) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions