Anaesthesia for peculiar cells'a century of sickle cell disease

Slides:

Advertisements

Similar presentations

2015 Alzheimer's disease facts and figures Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 11, Issue 3, Pages (March.

Advertisements

EASL Clinical Practice Guidelines: Vascular diseases of the liver Journal of Hepatology Volume 64, Issue 1, Pages (January 2016) DOI: /j.jhep

S. Sulaiman Shoab, MD, FCPS, FRCS, J. H. Scurr, MS, FRCS, P. D

Crises in Sickle Cell Disease

Inflammasomes in liver diseases

Human factors in anaesthesia: lessons from aviation

Maternal deaths from anaesthesia

T. Tedore British Journal of Anaesthesia

Pain in cancer survivors; filling in the gaps

Sun D. A. , Warriner C. B. , Parsons D. G. , Klein R. , Umedaly H. S

Why is the surgical high-risk patient still at risk?

Supplemental oxygen and surgical site infection: getting to the truth

Characteristics of pain in hospitalized medical patients, surgical patients, and outpatients attending a pain management centre M.P. Rockett, G. Simpson,

Antiemetic and analgesic-sparing effects of diphenhydramine added to morphine intravenous patient-controlled analgesia T.-F. Lin, Y.-C. Yeh, Y.-H. Yen,

Parkinson's disease and anaesthesia

J Barbara, M.-C. Santais, D.A. Levy, F Ruff, F Leynadier

K.-Y. Ho, W Tay, M.-C. Yeo, H Liu, S.-J. Yeo, S.-L. Chia, N.-N. Lo

G Turner, M.J. Goldacre, T Lambert, J.W. Sear

Inflammatory response, immunosuppression, and cancer recurrence after perioperative blood transfusions J.P. Cata, H. Wang, V. Gottumukkala, J. Reuben,

A different use of visual analytic techniques in anaesthetics

S.J. Howell, J.J. Pandit, D.J. Rowbotham

Assessment of the cough reflex after propofol anaesthesia for colonoscopy J Guglielminotti, T Rackelboom, A Tesniere, X Panhard, F Mentre, M Bonay, J.

Chronic opioid therapy for non-cancer pain

M.A. Olympio, R. Whelan, R.P.A. Ford, I.C.M. Saunders

Volume 130, Issue 6, (September 2007)

Glycopyrrolate during sevoflurane–remifentanil-based anaesthesia for cardiac catheterization of children with congenital heart disease K. Reyntjens,

Neuromuscular junction in health and disease

Effect of postoperative analgesia on surgical outcome

Does regional anaesthesia improve outcome after total hip arthroplasty

Development of acute tolerance to the EEG effect of propofol in rats†

Do team processes really have an effect on clinical performance

Expertise in practice: an ethnographic study exploring acquisition and use of knowledge in anaesthesia A. Smith, D. Goodwin, M. Mort, C. Pope British.

Coagulopathy and blood component transfusion in trauma

Procalcitonin, interleukin 6 and systemic inflammatory response syndrome (SIRS): early markers of postoperative sepsis after major surgery D Mokart,

Emergency surgical airway management in Denmark: a cohort study of patients registered in the Danish Anaesthesia Database C.V. Rosenstock, A.K.

Preoperative evaluation of patients with, or at risk of, coronary artery disease undergoing non-cardiac surgery P.-G. Chassot, A. Delabays, D.R. Spahn

Anaesthesia for awake craniotomy—evolution of a technique that facilitates awake neurological testing A. Sarang, J. Dinsmore British Journal of Anaesthesia

FastrachTM tubes: modifying the design for use with the LMA CTrachTM?

Distraction and interruption in anaesthetic practice

Tracheo-innominate artery fistula after percutaneous tracheostomy: three case reports and a clinical review C.A. Grant, G Dempsey, J Harrison, T Jones

I. Volikas, A. Butwick, C. Wilkinson, A. Pleming, G. Nicholson

Molecular Therapy Volume 18, Pages S260-S261 (May 2010) DOI: /S (16)

Normalization of acceleromyographic train-of-four ratio by baseline value for detecting residual neuromuscular block T Suzuki, N Fukano, O Kitajima,

Interstitial muscle concentrations of rocuronium under steady-state conditions in anaesthetized dogs: actual versus predicted values Ezzine S. , Varin.

Reviewer Acknowledgment

Acute traumatic coagulopathy: pathophysiology and resuscitation

Measurement of surgical stress in anaesthetized children

Tissue oxygen tension (PTO2) in anaesthesia and perioperative medicine

Reduction in mouth opening with semi-rigid cervical collars†

Securing tracheal tubes in facial burns

Is sickle cell disease a possible risk factor for peripheral neuropathy after popliteal sciatic nerve block? M Giabicani, V Compère, V Fourdrinier, B.

Teamwork, communication, and anaesthetic assistance in Scotland

Editorial II: Opioids and the neuroimmune axis

Usefulness of the carina as a radiographic landmark for central venous catheter placement in paediatric patients† S.Z. Yoon, J.H. Shin, S. Hahn, A.Y.

Chronic widespread pain, including fibromyalgia: a pathway for care developed by the British Pain Society J. Lee, B. Ellis, C. Price, A.P. Baranowski

Anil K. Saxena, MD, B.R. Panhotra, MD, PhD, MNAMS

Influence of muscle relaxation on neuromonitoring of the recurrent laryngeal nerve during thyroid surgery F. Marusch, J. Hussock, G. Haring, T. Hachenberg,

P.E. Vlisides, M.S. Avidan, G.A. Mashour

Regional anaesthesia to improve pain outcomes in paediatric surgical patients: a qualitative systematic review of randomized controlled trials S. Suresh,

Another case of obstruction to an anaesthetic circuit

Intraoperative oesophageal Doppler guided fluid management shortens postoperative hospital stay after major bowel surgery H.G. Wakeling, M.R. McFall,

Cricoid pressure force retention analysis using a simulator

Influence of head and neck position on ventilation using the air-Q® SP airway in anaesthetized paralysed patients: a prospective randomized crossover.

Influence of perioperative anaesthetic and analgesic interventions on oncological outcomes: a narrative review T. Wall, A. Sherwin, D. Ma, D.J. Buggy

Postoperative residual neuromuscular block: a survey of management

Minimum effective local anaesthetic dose of isobaric levobupivacaine and ropivacaine administered via a spinal catheter for hip replacement surgery Sell.

Effect of concentration of local anaesthetic solution on the ED50 of bupivacaine for supraclavicular brachial plexus block† P.K. Gupta, P.M. Hopkins

Volume 134, Issue 6, (September 2008)

This Month in AJKD American Journal of Kidney Diseases

R. Parke, S. McGuinness, R. Dixon, A. Jull

Presentation transcript:

Anaesthesia for peculiar cells'a century of sickle cell disease P.G. Firth British Journal of Anaesthesia Volume 95, Issue 3, Pages 287-299 (September 2005) DOI: 10.1093/bja/aei129 Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

Fig 1 The anaesthetic ‘vicious cycle’ hypothesis suggests that any condition that leads to increased sickling causes venous sludging, exacerbating sickling and creating a vicious cycle of further flow impairment, hypoxia, sickling, stasis, ischaemia, and infarction. British Journal of Anaesthesia 2005 95, 287-299DOI: (10.1093/bja/aei129) Copyright © 2005 British Journal of Anaesthesia Terms and Conditions

Fig 2 The ‘vascular inflammation’ hypothesis suggests that vaso-occlusion is triggered and propagated largely by alterations in the chronically disrupted cellular, plasma, and vascular components of haemostasis, rather than by fluctuations in sickling. Sickle cell disease causes chronic vascular inflammation, and triggers such as surgical stress produce pathological haemostatic responses. Abbreviations: A = adenine, G = guanine, T = thymine, IL-1, IL-6 = interleukin 1 and 6, TNF = tumour necrosis factor. British Journal of Anaesthesia 2005 95, 287-299DOI: (10.1093/bja/aei129) Copyright © 2005 British Journal of Anaesthesia Terms and Conditions