Volume 75, Issue 5, Pages (March 2009)

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Volume 75, Issue 5, Pages 542-549 (March 2009) Nocturnal hemodialysis does not improve overall measures of quality of life compared to conventional hemodialysis Braden J. Manns, Michael W. Walsh, Bruce F. Culleton, Brenda Hemmelgarn, Marcello Tonelli, Melissa Schorr, Scott Klarenbach Kidney International Volume 75, Issue 5, Pages 542-549 (March 2009) DOI: 10.1038/ki.2008.639 Copyright © 2009 International Society of Nephrology Terms and Conditions

Figure 1 Trial flow. Kidney International 2009 75, 542-549DOI: (10.1038/ki.2008.639) Copyright © 2009 International Society of Nephrology Terms and Conditions

Figure 2 In-trial EQ-5D scores. (a) EQ-5D index scores for nocturnal hemodialysis and conventional hemodialysis during the RCT. (b) EQ-5D visual analog scores for nocturnal hemodialysis and conventional hemodialysis during the RCT. Kidney International 2009 75, 542-549DOI: (10.1038/ki.2008.639) Copyright © 2009 International Society of Nephrology Terms and Conditions

Figure 3 The change in relevant Kidney-Disease-Specific Quality of Life Domains comparing 6 months and study baseline. Kidney International 2009 75, 542-549DOI: (10.1038/ki.2008.639) Copyright © 2009 International Society of Nephrology Terms and Conditions

Figure 4 Quality of life after completion of RCT during extended followup. (a) EQ-5D index scores during extended follow-up for patients remaining on nocturnal hemodialysis, conventional hemodialysis, and those switching from nocturnal hemodialysis to conventional hemodialysis, or from conventional hemodialysis to nocturnal hemodialysis. (b) The change in relevant Kidney-Disease-Specific Quality of Life Domains comparing May 2007 and RCT completion for patients remaining on nocturnal hemodialysis, conventional hemodialysis, and those switching from nocturnal hemodialysis to conventional hemodialysis, or from conventional hemodialysis to nocturnal hemodialysis (Note: bars above zero represent improvement in quality of life comparing May 2007 and RCT completion). Kidney International 2009 75, 542-549DOI: (10.1038/ki.2008.639) Copyright © 2009 International Society of Nephrology Terms and Conditions