Beware: shifting paradigms ahead

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Presentation transcript:

Beware: shifting paradigms ahead Randall Ellis Morris, MD The Lancet Volume 348, (December 1996) DOI: 10.1016/S0140-6736(96)98036-8 Copyright © 1996 Elsevier Ltd Terms and Conditions

Figure Therapeutic index of immunosuppression shown as a balance between efficacy and toxicity Cyclosporine and newer immunosuppressants have been responsible for progressively less acute rejection and less toxicity (defined by the combined incidences of malignancy and infection). The Lancet 1996 348, DOI: (10.1016/S0140-6736(96)98036-8) Copyright © 1996 Elsevier Ltd Terms and Conditions