a b c d e Moriguchi et al., Supplementary Fig. S1

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a b c d e Moriguchi et al., Supplementary Fig. S1 Latency on retention trials (s) a b c d e Discrimination index (%) Latency on first trials (s) Total arm entries Alternations (%) Moriguchi et al., Supplementary Fig. S1

a b c Moriguchi et al., Supplementary Fig. S2 fEPSP slope (% of cont) fEPSP amplitude (mV) Moriguchi et al., Supplementary Fig. S2

a b Moriguchi et al., Supplementary Fig. S3 Phosphorylation (% of cont) Moriguchi et al., Supplementary Fig. S3

a b Moriguchi et al., Supplementary Fig. S4

a b Moriguchi et al., Supplementary Fig. S5 K+ current (pA) Cont Mem Pin 50 pA Moriguchi et al., Supplementary Fig. S5

a b Moriguchi et al., Supplementary Fig. S6 Kir6.1 NeuN Merged Kir6.2 MAP2 Merged Kir6.2 MAP2 Merged Kir6.1 GFAP Merged Kir6.2 GFAP Merged Moriguchi et al., Supplementary Fig. S6

a b c Moriguchi et al., Supplementary Fig. S7 Protein levels (% of cont) Protein levels (% of cont) Moriguchi et al., Supplementary Fig. S7

a b c d e f g h i Moriguchi et al., Supplementary Fig. S8 Latency on retention trials (s) a b c Discrimination index (%) d Latency on first trials (s) e Total arm entries Alternations (%) f g h i Protein levels (% of cont) fEPSP slope (% of cont) fEPSP slope (% of cont) Moriguchi et al., Supplementary Fig. S8

a b c Moriguchi et al., Supplementary Fig. S9 Phosphorylation (% of cont) Protein levels (% of cont) Moriguchi et al., Supplementary Fig. S9

a b c d e f g Moriguchi et al., Supplementary Fig. S10 Latency on retention trials (s) a b c d e Discrimination index (%) Latency on first trials (s) Total arm entries Alternations (%) f g fEPSP slope (% of cont) fEPSP slope (% of cont) Moriguchi et al., Supplementary Fig. S10

a b c d Moriguchi et al., Supplementary Fig. S11 fEPSP slope (% of cont) fEPSP slope (% of cont) c d Phosphorylation (% of cont) Moriguchi et al., Supplementary Fig. S11

a b Moriguchi et al., Supplementary Fig. S12 Phosphorylation (% of cont) Moriguchi et al., Supplementary Fig. S12

a b c d Moriguchi et al., Supplementary Fig. S13 Immobility time (s) Number of BrdU-positive cells/ area Moriguchi et al., Supplementary Fig. S13

a b c d Moriguchi et al., Supplementary Fig. S14 Immobility time (s) Number of BrdU-positive cells/ area Moriguchi et al., Supplementary Fig. S14

Moriguchi et al., Supplementary Fig. 15 Blood glucose levels (mg/dl) Moriguchi et al., Supplementary Fig. 15