Volume 57, Issue 1, Pages (January 2000)

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Volume 57, Issue 1, Pages 224-231 (January 2000) Renal hemodynamics and pharmacokinetics of bosentan with and without cyclosporine A Isabelle Binet, M.D., Andreas Wallnöfer, Cornelia Weber, Richard Jones, Gilbert Thiel Kidney International Volume 57, Issue 1, Pages 224-231 (January 2000) DOI: 10.1046/j.1523-1755.2000.00838.x Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 1 Study design. Kidney International 2000 57, 224-231DOI: (10.1046/j.1523-1755.2000.00838.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 2 Systolic/diastolic blood pressure. Mean results (± SEM) of hourly blood pressure measurements during clearance assessment after placebo (•; baseline), seven days of CsA + placebo (▴), and seven days of CsA + BO regular intake (▪). Kidney International 2000 57, 224-231DOI: (10.1046/j.1523-1755.2000.00838.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 3 Glomerular filtration rate. Mean results (± SEM) of hourly inulin clearance after placebo (•; baseline), seven days of CsA + placebo (▴), and seven days of CsA + BO regular intake (▪). Kidney International 2000 57, 224-231DOI: (10.1046/j.1523-1755.2000.00838.x) Copyright © 2000 International Society of Nephrology Terms and Conditions

Figure 4 Renal plasma flow. Mean results (± SEM) of hourly PAH clearance after placebo (•; baseline), seven days of CsA + placebo (▴), and seven days of CsA + BO regular intake (▪). Kidney International 2000 57, 224-231DOI: (10.1046/j.1523-1755.2000.00838.x) Copyright © 2000 International Society of Nephrology Terms and Conditions