Arman Qamar et al. JACC 2018;71:

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Arman Qamar et al. JACC 2018;71:2162-2175 Management of Severe or Life-Threatening Bleeding in Patients With Liver Disease Who Are Taking OACs ACC = American College of Cardiology; aPTT = activated partial thromboplastin time; CBC = complete blood count; EGD = esophagogastroduodenoscopy; FXa = factor Xa; INR = international normalized ratio; IV = intravenous; LFTs = liver function tests; OAC = oral anticoagulant agent; PT = prothrombin time; TIPS = transjugular intrahepatic portosystemic shunt; 4F-PCC = 4 factor-prothrombin complex concentrate; 2° = secondary. Arman Qamar et al. JACC 2018;71:2162-2175 2018 American College of Cardiology Foundation