Comparison of pH management during antegrade selective cerebral perfusion in canine models with old cerebral infarction  Kazuhiro Ohkura, MD, Teruhisa.

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Presentation transcript:

Comparison of pH management during antegrade selective cerebral perfusion in canine models with old cerebral infarction  Kazuhiro Ohkura, MD, Teruhisa Kazui, MD, Seiji Yamamoto, MD, PhD, Katsushi Yamashita, MD, Hitoshi Terada, MD, Naoki Washiyama, MD, Takayasu Suzuki, MD, Kazuchika Suzuki, MD, Michio Fujie, MS, Kentaro Ohishi, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 128, Issue 3, Pages 378-385 (September 2004) DOI: 10.1016/j.jtcvs.2003.11.031

Figure 1 Levels of VALD. The values are shown according to the time course (see in text). In group C VALD significantly increased at time course 3. *P < .05, different from groups A and B. Values are expressed as means ± SE. The Journal of Thoracic and Cardiovascular Surgery 2004 128, 378-385DOI: (10.1016/j.jtcvs.2003.11.031)

Figure 2 Changes of serum MDA concentration. The percentages of preoperative value are shown according to the time course (see in text). In group C the value significantly increased from time course 6 to time course 8. *P < .05, different from groups A and B; #P < .01, different from groups A and B. Values are expressed as means ± SE. The Journal of Thoracic and Cardiovascular Surgery 2004 128, 378-385DOI: (10.1016/j.jtcvs.2003.11.031)

Figure 3 Changes of serum glutamate concentration. The percentages of preoperative value are shown according to the time course (see in text). The concentration significantly increased in group C after time course 7. *P < .05, different from groups A and B; #P < .01, different from groups A and B. Values are expressed as means ± SE. The Journal of Thoracic and Cardiovascular Surgery 2004 128, 378-385DOI: (10.1016/j.jtcvs.2003.11.031)

Figure 4 Changes in CCT after surgical intervention. The percentages of preoperative CCT are shown. In group C, CCT was significantly prolonged after the operation. In group D, CCT tended to increase, but it did not reach a significant level. *P < .05, different from groups A and B. Values are expressed as means ± SE. The Journal of Thoracic and Cardiovascular Surgery 2004 128, 378-385DOI: (10.1016/j.jtcvs.2003.11.031)

Figure 5 Changes in N4/N1 ratio after surgical intervention The percentages of the preoperative N4/N1 ratio are shown. In groups C and D the N4/N1 ratio significantly decreased after the operation. *P < .05, different from groups A and B. Values are expressed as means ± SE. The Journal of Thoracic and Cardiovascular Surgery 2004 128, 378-385DOI: (10.1016/j.jtcvs.2003.11.031)