The effect of right ventricular myocardial remodeling on ventricular function as assessed by two-dimensional speckle tracking echocardiography in patients.

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The effect of right ventricular myocardial remodeling on ventricular function as assessed by two-dimensional speckle tracking echocardiography in patients with tetralogy of Fallot: A single center experience from China Mingxing Xie, Yuman Li, Tsung O. Cheng, Xinfang Wang, Nianguo Dong, Xiu Nie, Qing Lu, YaLi Yang, Lin He, Ling Li, Pingping Ren International Journal of Cardiology Volume 178, Pages 300-307 (January 2015) DOI: 10.1016/j.ijcard.2014.10.027 Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 The right ventricular (RV) global longitudinal strain and strain rate curves in patients with tetralogy of Fallot (TOF) (A, B). The white dotted curves represent the RV global longitudinal strain and strain rate. GLS: global longitudinal peak systolic strain; GLSRs: global longitudinal peak systolic strain rate; GLSRe: global longitudinal peak early diastolic strain rate. International Journal of Cardiology 2015 178, 300-307DOI: (10.1016/j.ijcard.2014.10.027) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 The cardiomyocyte diameters (A) and interstitial collagen content (B) in hearts with TOF and controls. The reference values of the control group were obtained from the literature[1,10–12]. CVF: collagen volume fraction. *P<0.05 versus the control group. International Journal of Cardiology 2015 178, 300-307DOI: (10.1016/j.ijcard.2014.10.027) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 3 Comparisons of the histopathological parameters between younger and older patients with TOF. CVF: collagen volume fraction. *P<0.05 versus the younger subgroup. International Journal of Cardiology 2015 178, 300-307DOI: (10.1016/j.ijcard.2014.10.027) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 4 Correlations between the patient age at the time of the surgical repair of TOF and the cardiomyocyte diameters (A), endocardial thickness (B) and interstitial collagen content (C). CVF: collagen volume fraction. International Journal of Cardiology 2015 178, 300-307DOI: (10.1016/j.ijcard.2014.10.027) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 5 Comparisons of the RV GLS (A), GLSRs (B) and GLSRe (C) between the preoperative and postoperative patients with TOF. *P<0.05 versus the preoperative patients. International Journal of Cardiology 2015 178, 300-307DOI: (10.1016/j.ijcard.2014.10.027) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 6 Correlations between the histopathological parameters and the preoperative RV GLS (A, B) and GLSRe (C) in the younger subgroup. And the relationship between the histopathological parameters and the preoperative RV GLSRs (D, E) and GLSRe (F) in the older subgroup. CVF: collagen volume fraction. International Journal of Cardiology 2015 178, 300-307DOI: (10.1016/j.ijcard.2014.10.027) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 7 The association between the histopathological parameters and the postoperative RV GLS (A), GLSRs (C) and GLSRe (B, D) in the older subgroup. CVF: collagen volume fraction. International Journal of Cardiology 2015 178, 300-307DOI: (10.1016/j.ijcard.2014.10.027) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions