Liver, Muscle, and Adipose Tissue Insulin Action Is Directly Related to Intrahepatic Triglyceride Content in Obese Subjects Kevin M. Korenblat, Elisa.

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Presentation transcript:

Liver, Muscle, and Adipose Tissue Insulin Action Is Directly Related to Intrahepatic Triglyceride Content in Obese Subjects Kevin M. Korenblat, Elisa Fabbrini, B. Selma Mohammed, Samuel Klein Gastroenterology Volume 134, Issue 5, Pages 1369-1375 (May 2008) DOI: 10.1053/j.gastro.2008.01.075 Copyright © 2008 AGA Institute Terms and Conditions

Figure 1 Relationship between IAAT volume and IHTG content. Gastroenterology 2008 134, 1369-1375DOI: (10.1053/j.gastro.2008.01.075) Copyright © 2008 AGA Institute Terms and Conditions

Figure 2 Relationships between (1) hepatic insulin sensitivity and IHTG content (top panel), (2) insulin-mediated suppression of palmitate Ra during stage 1 of the euglycemic-hyperinsulinemic clamp procedure and IHTG content (middle panel), and (3) insulin-mediated stimulation of glucose uptake (glucose Rd) during stage 2 of the euglycemic-hyperinsulinemic clamp procedure and IHTG content (bottom panel). Gastroenterology 2008 134, 1369-1375DOI: (10.1053/j.gastro.2008.01.075) Copyright © 2008 AGA Institute Terms and Conditions