Ettore Cicinelli, M. D. , Louis J Ignarro, M. D. , Pietro Galantino, M

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Presentation transcript:

Effects of tibolone on plasma levels of nitric oxide in postmenopausal women Ettore Cicinelli, M.D., Louis J Ignarro, M.D., Pietro Galantino, M.D., Vincenzo Pinto, M.D., Bruno Barba, M.D., Sergio Schonauer, M.D. Fertility and Sterility Volume 78, Issue 3, Pages 464-468 (September 2002) DOI: 10.1016/S0015-0282(02)03295-8

FIGURE 1 Plasma levels of nitrite and nitrate, the nitric oxide (NO) stable metabolites, in nine women treated for 1 month with tibolone 2.5 mg/day and with placebo for the following month (group A) (solid bars) and in nine women receiving inverted treatment (group B) (open bars). Data are means + SD. An asterisk at month 1 indicates that the differences between NO mean values in group A and group B and between month 1 and baseline values in group A are statistically significant; conversely, an asterisk at month 2 indicates that levels in group B are higher than at baseline and in group A. Cicinelli. Tibolone and NO in menopausal women. Fertil Steril 2002. Fertility and Sterility 2002 78, 464-468DOI: (10.1016/S0015-0282(02)03295-8)