Association of Transcription-Coupled Repair but Not Global Genome Repair with Ultraviolet-B-Induced Langerhans Cell Depletion and Local Immunosuppression  Wendy Kölgen, Harry van Steeg, Gijsbertus T.J. van der Horst, Jan H.J. Hoeijmakers, Willem A. van Vloten, Frank R. de Gruijl, Johan Garssen  Journal of Investigative Dermatology  Volume 121, Issue 4, Pages 751-756 (October 2003) DOI: 10.1046/j.1523-1747.2003.12476.x Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 UV-induced local immunosuppression of CHS in XPA mice (white bars) and wild-type littermates (black bars). Each bar represents net ear swelling (mean±SEM). The ear swelling in sensitized unirradiated mice was set at 100%. p<0.001 (1). Journal of Investigative Dermatology 2003 121, 751-756DOI: (10.1046/j.1523-1747.2003.12476.x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 2 UV-induced local immunosuppression of CHS in CSB mice (white bars) and wild-type littermates (black bars). Each bar represents net ear swelling (mean±SEM). The ear swelling in sensitized unirradiated mice was set at 100%. p<0.001 (1+2). Journal of Investigative Dermatology 2003 121, 751-756DOI: (10.1046/j.1523-1747.2003.12476.x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 3 UV-induced local immunosuppression of CHS in XPC mice (white bars) and wild-type littermates (black bars). Each bar represents net ear swelling (mean±SEM). The ear swelling in sensitized unirradiated mice was set at 100%. p<0.001 (1); p<0.01 (2). Journal of Investigative Dermatology 2003 121, 751-756DOI: (10.1046/j.1523-1747.2003.12476.x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 4 Percentage of epidermal NLDC145+ area (mean±SEM) of the (un)exposed ear skin of XPA mice (white bars) and wild-type littermates (black bars). p=0.011 (1); p=0.012 (2). Journal of Investigative Dermatology 2003 121, 751-756DOI: (10.1046/j.1523-1747.2003.12476.x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 5 Percentage of epidermal NLDC145+ area (mean±SEM) of the (un)exposed ear skin of CSB mice (white bars) and wild-type littermates (black bars). p<0.001 (1); p=0.001 (2); p=0.009 (3); p=0.008 (4); p=0.017 (5). Journal of Investigative Dermatology 2003 121, 751-756DOI: (10.1046/j.1523-1747.2003.12476.x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 6 Percentage of epidermal NLDC145+ area (mean±SEM) of the (un)exposed ear skin of XPC mice (white bars) and wild-type littermates (black bars). p=0.006 (1); p=0.015 (2). Journal of Investigative Dermatology 2003 121, 751-756DOI: (10.1046/j.1523-1747.2003.12476.x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions